This review aims to present the issues associated to enantioseparation of chiral
pharmaceuticals in biological and environmental matrices using chiral stationary phases …

This paper reviews analytical approaches published in 2002–2012 for chiral drug analysis
and their relevance in research and practice in the field of clinical and forensic toxicology …

Abstract Development of a robust HPLC method for pharmaceutical analysis can be very
challenging and time-consuming. In our laboratory, we have developed a new workflow …

New, sensitive and rapid chiral HPLC method for enantioseparation and determination of
widely used hypnotic drug, zopiclone, was developed. Enantioseparation was achieved on …

A rapid, sensitive, and enantioselective method was developed and validated for
determination of ornidazole enantiomers in human plasma by liquid chromatography …

A procedure for the determination of Eszopiclone (ESZ) from complex matrices ie in vitro
(spiked matrices), as well as in vivo (mice model) was developed using cloud point …

In order to meet the drug discovery and development needs of pharmaceutical companies,
CROs are constantly challenged by the requirements for rapid LC–MS/MS method …

Detecting z-drugs, a sedative-hypnotic medication, is also misused for criminal activities.
Therefore, the analysis of urine samples is crucial for clinical and forensic purposes. We …

Zopiclone and its (S)-enantiomer (eszopiclone) are commonly prescribed for insomnia.
Despite the high demand for enantioselective differentiation, the chiral analysis of zopiclone …

Electrochemical‐ion‐selective‐sensors offer green, rapid, economic and simple analytical‐
tool in pharmaceutical industry, control processes, physiological measurements and …