The 2‐Pyridyl Problem: Challenging Nucleophiles in Cross‐Coupling Arylations

XAF Cook, A de Gombert, J McKnight… - Angewandte …, 2021 - Wiley Online Library
Azine‐containing biaryls are ubiquitous scaffolds in many areas of chemistry, and efficient
methods for their synthesis are continually desired. Pyridine rings are prominent amongst …

Applications of and alternatives to π-electron-deficient azine organometallics in metal catalyzed cross-coupling reactions

LC Campeau, K Fagnou - Chemical Society Reviews, 2007 - pubs.rsc.org
While the use of π-deficient azine halides in palladium catalyzed cross-coupling reactions is
common, the use of π-electron deficient azine organometallics has been less intensively …

Functionalization of diazines and benzo derivatives through deprotonated intermediates

F Chevallier, F Mongin - Chemical Society Reviews, 2008 - pubs.rsc.org
This critical review targets as a readership researchers generally oriented toward organic
synthesis and in particular those active in heterocyclic chemistry. Diazines and benzo …

Trifluoromethyl-substituted iridium (III) complexes: from photophysics to photooxidation of a biological target

R Bevernaegie, L Marcélis, B Laramée-Milette… - Inorganic …, 2018 - ACS Publications
Photodynamic therapeutic agents are of key interest in developing new strategies to develop
more specific and efficient anticancer treatments. In comparison to classical …

Synthesis of 2, 2′‐bipyridyl‐type compounds via the suzuki‐miyaura cross‐coupling reaction

NA Jones, JW Antoon, AL Bowie, JB Borak… - Journal of Heterocyclic …, 2007 - cir.nii.ac.jp
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[PDF][PDF] Metalated heterocycles in organic synthesis: Recent applications

R Chinchilla, C Nájera, M Yus - 2007 - rua.ua.es
TITLE (Word Style “A_Title”) Page 1 Issue in Honor of Prof. Alain Krief ARKIVOC 2007 (x)
152-231 Metalated heterocycles in organic synthesis: recent applications Rafael Chinchilla …

Synthesis of Functionalized Pyridazin-3(2H)-ones via Bromine−Magnesium Exchange on Bromopyridazin-3(2H)-ones

O Ryabtsova, T Verhelst, M Baeten… - The Journal of …, 2009 - ACS Publications
The potential of halogen− magnesium exchange reactions, followed by quenching with
electrophiles, for the functionalization of the pyridazin-3 (2 H)-one core was investigated. 2 …

Pd‐Catalyzed Chemoselective Cross‐Coupling Reaction of Triaryl‐or Triheteroarylbismuth Compounds with 3, 6‐Dihalopyridazines

K Urgin, C Aubé, M Pipelier, V Blot… - European Journal of …, 2013 - Wiley Online Library
The cross‐coupling reactions of 3, 6‐dihalopyridazines with triaryl‐or triheteroarylbismuth
compounds were performed under palladium catalysis. The reaction was highly …

A Novel and Highly Regioselective Route to Construct Methylthio-Substituted Pyridazines from Aryl Methyl Ketones at Room Temperature

L Wu, Y Yang, M Gao, D Zhang, W Shu, Y Zhu, A Wu - Synlett, 2012 - thieme-connect.com
A novel and highly regioselective two-step homocoupling/cyclization procedure from easily
available aryl methyl ketones and hydrazine hydrate was developed for the synthesis of …

Metalation of Pyridazine, Cinnoline, and Phthalazine

E Horkel - Metalation of Azines and Diazines, 2013 - Springer
This chapter reviews the metalation of pyridazine, cinnoline, and phthalazine derivatives as
well as the usage of the hereby formed organometallic compounds in subsequent reactions …