Hereditary colorectal polyposis and cancer syndromes: a primer on diagnosis and management
P Kanth, J Grimmett, M Champine, R Burt… - Official journal of the …, 2017 - journals.lww.com
Colorectal cancer (CRC) is the fourth most common cancer amongst men and women.
Between 3 and 6% of all CRCs are attributed to well-defined inherited syndromes, including …
Between 3 and 6% of all CRCs are attributed to well-defined inherited syndromes, including …
Molecular pathways in colorectal cancer
Colorectal cancer (CRC) is the second most common newly diagnosed cancer and accounts
for the second highest number of cancer related deaths in Australia, the third worldwide and …
for the second highest number of cancer related deaths in Australia, the third worldwide and …
Gene-panel sequencing and the prediction of breast-cancer risk
Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
[HTML][HTML] Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the clinical practice of hereditary colorectal cancer
N Tomita, H Ishida, K Tanakaya, T Yamaguchi… - International Journal of …, 2021 - Springer
Hereditary colorectal cancer (HCRC) accounts for< 5% of all colorectal cancer cases. Some
of the unique characteristics commonly encountered in HCRC cases include early age of …
of the unique characteristics commonly encountered in HCRC cases include early age of …
Guidelines for the clinical management of familial adenomatous polyposis (FAP)
HFA Vasen, G Moeslein, A Alonso, S Aretz, I Bernstein… - Gut, 2008 - gut.bmj.com
Background: Familial adenomatous polyposis (FAP) is a well-described inherited syndrome,
which is responsible for< 1% of all colorectal cancer (CRC) cases. The syndrome is …
which is responsible for< 1% of all colorectal cancer (CRC) cases. The syndrome is …
Expanded extracolonic tumor spectrum in MUTYH-associated polyposis
S Vogt, N Jones, D Christian, C Engel, M Nielsen… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: MUTYH-associated polyposis (MAP) is characterized by a lifetime
risk of colorectal cancer of up to 100%. However, no systematic evaluation of extracolonic …
risk of colorectal cancer of up to 100%. However, no systematic evaluation of extracolonic …
Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH
Germline mutations in the DNA base excision repair gene MUTYH are known to increase a
carrier's risk of colorectal cancer. However, the risks of other (extracolonic) cancers for …
carrier's risk of colorectal cancer. However, the risks of other (extracolonic) cancers for …
The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management
ML Leoz, S Carballal, L Moreira, T Ocaña… - The application of …, 2015 - Taylor & Francis
Familial adenomatous polyposis (FAP) is an inherited disorder that represents the most
common gastrointestinal polyposis syndrome. Germline mutations in the APC gene were …
common gastrointestinal polyposis syndrome. Germline mutations in the APC gene were …
MUTYH-associated polyposis (MAP)
The human mutY homologue (MUTYH) gene is responsible for inheritable polyposis and
colorectal cancer. This review discusses the molecular genetic aspects of the MUTYH gene …
colorectal cancer. This review discusses the molecular genetic aspects of the MUTYH gene …
Hyperplastic polyps and sessile serrated adenomas as a phenotypic expression of MYH-associated polyposis
KS Boparai, E Dekker, S Van Eeden, MM Polak… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS:: MYH-associated polyposis (MAP) is a disorder caused by a bi-
allelic germline MYH mutation, characterized by multiple colorectal adenomas. These …
allelic germline MYH mutation, characterized by multiple colorectal adenomas. These …