Survivors of childhood and adolescent cancer: life-long risks and responsibilities

LL Robison, MM Hudson - Nature Reviews Cancer, 2014 - nature.com
Survival rates for most paediatric cancers have improved at a remarkable pace over the past
four decades. In developed countries, cure is now the probable outcome for most children …

Improving quality and quantity of life for childhood cancer survivors globally in the twenty-first century

MJ Ehrhardt, KR Krull, N Bhakta, Q Liu… - Nature Reviews …, 2023 - nature.com
The contributions of cooperative groups to performing large-cohort clinical trials and long-
term survivorship studies have facilitated advances in treatment, supportive care and …

Specific causes of excess late mortality and association with modifiable risk factors among survivors of childhood cancer: a report from the Childhood Cancer Survivor …

SB Dixon, Q Liu, EJ Chow, KC Oeffinger, PC Nathan… - The Lancet, 2023 - thelancet.com
Background 5-year survival after childhood cancer does not fully describe life-years lost due
to childhood cancer because there are a large number of deaths occurring beyond 5-years …

Late mortality and chronic health conditions in long-term survivors of early-adolescent and young adult cancers: a retrospective cohort analysis from the Childhood …

E Suh, KL Stratton, WM Leisenring, PC Nathan… - The Lancet …, 2020 - thelancet.com
Background Treatment outcomes among survivors of cancer diagnosed during adolescence
and early young adulthood have not been characterised independently of survivors of …

St. Jude Cloud: a pediatric cancer genomic data-sharing ecosystem

C McLeod, AM Gout, X Zhou, A Thrasher, D Rahbarinia… - Cancer discovery, 2021 - AACR
Effective data sharing is key to accelerating research to improve diagnostic precision,
treatment efficacy, and long-term survival in pediatric cancer and other childhood …

Reduction in late mortality among 5-year survivors of childhood cancer

GT Armstrong, Y Chen, Y Yasui… - … England Journal of …, 2016 - Mass Medical Soc
Background Among patients in whom childhood cancer was diagnosed in the 1970s and
1980s, 18% of those who survived for 5 years died within the subsequent 25 years. In recent …

Survivors of childhood cancer in the United States: prevalence and burden of morbidity

SM Phillips, LS Padgett, WM Leisenring… - … Biomarkers & Prevention, 2015 - AACR
Background: No studies have estimated the population-level burden of morbidity in
individuals diagnosed with cancer as children (ages 0–19 years). We updated prevalence …

Temporal patterns in the risk of chronic health conditions in survivors of childhood cancer diagnosed 1970–99: a report from the Childhood Cancer Survivor Study …

TM Gibson, S Mostoufi-Moab, KL Stratton… - The Lancet …, 2018 - thelancet.com
Background Treatments for childhood cancer have evolved over the past 50 years, with the
goal of maximising the proportion of patients who achieve long-term survival, while …

Modifiable risk factors and major cardiac events among adult survivors of childhood cancer

GT Armstrong, KC Oeffinger, Y Chen… - Journal of clinical …, 2013 - ascopubs.org
Purpose To evaluate the relative contribution of modifiable cardiovascular risk factors on the
development of major cardiac events in aging adult survivors of childhood cancer. Patients …

Aging and risk of severe, disabling, life-threatening, and fatal events in the childhood cancer survivor study

GT Armstrong, T Kawashima, W Leisenring… - Journal of clinical …, 2014 - ascopubs.org
Purpose The first generation of childhood cancer survivors is now aging into their fourth and
fifth decades of life, yet health risks across the aging spectrum are not well established …