The microbiome of the upper respiratory tract in health and disease

C Kumpitsch, K Koskinen, V Schöpf… - BMC biology, 2019 - Springer
The human upper respiratory tract (URT) offers a variety of niches for microbial colonization.
Local microbial communities are shaped by the different characteristics of the specific …

Endotype-driven treatment in chronic upper airway diseases

G De Greve, PW Hellings, WJ Fokkens, B Pugin… - Clinical and translational …, 2017 - Springer
Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease.
Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30 …

European position paper on rhinosinusitis and nasal polyps 2012

WJ Fokkens, VI Lund, J Mullol, C Bachert, I Alobid… - Rhinology, 2012 - biblio.ugent.be
The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

ICON: chronic rhinosinusitis

C Bachert, R Pawankar, L Zhang, C Bunnag… - World Allergy …, 2014 - Springer
Chronic rhinosinusitis (CRS) is a public health problem that has a significant socio-
economic impact. Moreover, the complexity of this disease due to its heterogeneous nature …

The microbiome of chronic rhinosinusitis: culture, molecular diagnostics and biofilm detection

S Boase, A Foreman, E Cleland, L Tan… - BMC infectious …, 2013 - Springer
Background Bacteria and fungi are believed to influence mucosal inflammation in chronic
rhinosinusitis (CRS). However their presence and relationship to disease is debated. This …

Evidence of microbiota dysbiosis in chronic rhinosinusitis

M Hoggard, K Biswas, M Zoing… - International forum of …, 2017 - Wiley Online Library
Background Despite considerable research, the pathogenesis of chronic rhinosinusitis
(CRS) remains poorly understood. Potential microbial roles in the etiology or progression of …

[HTML][HTML] Comprehensive review on endonasal endoscopic sinus surgery

RK Weber, W Hosemann - GMS current topics in …, 2015 - ncbi.nlm.nih.gov
Endonasal endoscopic sinus surgery is the standard procedure for surgery of most
paranasal sinus diseases. Appropriate frame conditions provided, the respective procedures …

Biofilm aggregates and the host airway-microbial interface

L Hall-Stoodley, KS McCoy - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Biofilms are multicellular microbial aggregates that can be associated with host mucosal
epithelia in the airway, gut, and genitourinary tract. The host environment plays a critical role …

Kaempferol Inhibits the Primary Attachment Phase of Biofilm Formation in Staphylococcus aureus

D Ming, D Wang, F Cao, H Xiang, D Mu, J Cao… - Frontiers in …, 2017 - frontiersin.org
The ability to form biofilms on surfaces makes Staphylococcus aureus the main pathogenic
factor in implanted medical device infections. The aim of this study was to discover a biofilm …

The Role of Staphylococcus aureus in Patients with Chronic Sinusitis and Nasal Polyposis

TW Vickery, VR Ramakrishnan, JD Suh - Current allergy and asthma …, 2019 - Springer
Abstract Purpose of Review Staphylococcus aureus (S. aureus) is correlated with the
development of persistent severe inflammatory disease of the upper airway including …