Parkinson's disease (PD) is the second most common neurodegenerative disease, the main
pathological hallmark of which is the accumulation of α-synuclein (α-syn) and the formation …

Neurodegenerative diseases (NDDs) are characterized by selective dysfunction and loss of
neurons associated with pathologically altered proteins that deposit in the human brain but …

Abstract α-Synuclein is an abundantly expressed neuronal protein that is at the center of
focus in understanding a group of neurodegenerative disorders called α-synucleinopathies …

α-Synuclein is a presynaptic neuronal protein that is linked genetically and
neuropathologically to Parkinson's disease (PD). α-Synuclein may contribute to PD …

Olfactory deficits are present in numerous neurodegenerative disorders and are
accompanied by pathology in related brain regions. In several of these disorders, olfactory …

Abnormal neuronal aggregation of α-synuclein is implicated in the development of many
neurological disorders, including Parkinson disease and dementia with Lewy bodies. Glial …

The presence of Lewy bodies, mainly consisting of aggregated α-synuclein, is a pathological
hallmark of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The α …

Background Parkinson's disease (PD) is the most common movement disorder. While
neuronal deposition of α-synuclein serves as a pathological hallmark of PD and Dementia …

Neurodegenerative diseases (NDDs) originate from a loss of neurons in the central nervous
system and are severely debilitating. The incidence of NDDs increases with age, and they …

Astrocytic α-synuclein-immunoreactive inclusions have recently been noted to develop in
sporadic Parkinson's disease (PD). Here, the presence of immunoreactive astrocytes is …