Regulation of gut microbiota on immune cell ferroptosis: a novel insight for immunotherapy against tumor

R Liu, J Wang, Y Liu, Y Gao, R Yang - Cancer Letters, 2024 - Elsevier
Gut microbiota contributes to the homeostasis of immune system and is related to various
diseases such as tumorigenesis. Ferroptosis, a new type of cell death, is also involved in the …

[HTML][HTML] NFE2L2 and ferroptosis resistance in cancer therapy

D Tang, R Kang - Cancer Drug Resistance, 2024 - pmc.ncbi.nlm.nih.gov
NFE2-like basic leucine zipper transcription factor 2 (NFE2L2, also known as NRF2), is a
key transcription factor in the cellular defense against oxidative stress, playing a crucial role …

Photothermal Fe3O4 nanoparticles induced immunogenic ferroptosis for synergistic colorectal cancer therapy

Y Li, J Chen, Q Xia, J Shang, Y He, Z Li, Y Chen… - Journal of …, 2024 - Springer
Photothermal therapy (PTT) is a promising non-invasive treatment that has shown great
potential in eliminating tumors. It not only induces apoptosis of cancer cells but also triggers …

Emerging chemophysiological diversity of gut microbiota metabolites

X Lin, K He, Z Gu, X Zhao - Trends in Pharmacological Sciences, 2024 - cell.com
Human physiology is profoundly influenced by the gut microbiota, which generates a wide
array of metabolites. These microbiota-derived compounds serve as signaling molecules …

Gut microbial metabolism in ferroptosis and colorectal cancer

W Cui, M Hao, X Yang, C Yin, B Chu - Trends in Cell Biology, 2024 - cell.com
Ferroptosis is programmed cell death induced by iron-driven lipid peroxidation. Numerous
studies have shown that ferroptosis is implicated in the progression of colorectal cancer …

Gut microbial metabolites in cancer therapy

P Song, Z Peng, X Guo - Trends in Endocrinology & Metabolism, 2024 - cell.com
The gut microbiota plays a crucial role in maintaining homeostasis and promoting health. A
growing number of studies have indicated that gut microbiota can affect cancer …

Ferroptosis as a new tool for tumor suppression through lipid peroxidation

X Yang, Y Liu, Z Wang, Y Jin, W Gu - Communications Biology, 2024 - nature.com
As a newly defined type of programmed cell death, ferroptosis is considered a potent
weapon against tumors due to its distinct mechanism from other types of programmed cell …

The role of microbial indole metabolites in tumor

D Jia, Z Kuang, L Wang - Gut Microbes, 2024 - Taylor & Francis
The gut microbiota can produce a variety of microbial-derived metabolites to influence tumor
development. Tryptophan, an essential amino acid in the human body, can be converted by …

[HTML][HTML] Canagliflozin Inhibits Palmitic Acid-Induced Vascular Cell Aging In Vitro through ROS/ERK and Ferroptosis Pathways

F Wan, X He, W Xie - Antioxidants, 2024 - mdpi.com
Vascular aging is one of the reasons for the high incidence of cardiovascular diseases
nowadays, as vascular cells age due to various internal and external factors. Among them …

Ferroptosis at the nexus of metabolism and metabolic diseases

S Li, G Zhang, J Hu, Y Tian, X Fu - Theranostics, 2024 - pmc.ncbi.nlm.nih.gov
Ferroptosis, an iron-dependent form of regulated cell death, is emerging as a crucial
regulator of human physiology and pathology. Increasing evidence showcases a reciprocal …