[HTML][HTML] The intrinsic viscosity of biological macromolecules. Progress in measurement, interpretation and application to structure in dilute solution

SE Harding - Progress in biophysics and molecular biology, 1997 - Elsevier
The intrinsic viscosity of biological macromolecules. Progress in measurement, interpretation
and application to structure in dilute solution - ScienceDirect Skip to main contentSkip to article …

Dimers to Doughnuts:  Redox-Sensitive Oligomerization of 2-Cysteine Peroxiredoxins,

ZA Wood, LB Poole, RR Hantgan, PA Karplus - Biochemistry, 2002 - ACS Publications
2-Cys peroxiredoxins (Prxs) are a large and diverse family of peroxidases which, in addition
to their antioxidant functions, regulate cell signaling pathways, apoptosis, and differentiation …

The open AUC project

H Cölfen, TM Laue, W Wohlleben, K Schilling… - European Biophysics …, 2010 - Springer
Progress in analytical ultracentrifugation (AUC) has been hindered by obstructions to
hardware innovation and by software incompatibility. In this paper, we announce and outline …

[PDF][PDF] US-SOMO HPLC-SAXS module: dealing with capillary fouling and extraction of pure component patterns from poorly resolved SEC-SAXS data

E Brookes, P Vachette, M Rocco… - Journal of applied …, 2016 - journals.iucr.org
Size-exclusion chromatography coupled with SAXS (small-angle X-ray scattering), often
performed using a flow-through capillary, should allow direct collection of monodisperse …

An Iron-Binding Protein, Dpr, from Streptococcus mutans Prevents Iron-Dependent Hydroxyl Radical Formation In Vitro

Y Yamamoto, LB Poole, RR Hantgan… - Journal of …, 2002 - Am Soc Microbiol
The dpr gene is an antioxidant gene which was isolated from the Streptococcus mutans
chromosome by its ability to complement an alkyl hydroperoxide reductase-deficient mutant …

The implementation of SOMO (SOlution MOdeller) in the UltraScan analytical ultracentrifugation data analysis suite: enhanced capabilities allow the reliable …

E Brookes, B Demeler, C Rosano, M Rocco - European Biophysics Journal, 2010 - Springer
The interpretation of solution hydrodynamic data in terms of macromolecular structural
parameters is not a straightforward task. Over the years, several approaches have been …

SOMO (SOlution MOdeler): differences between X-ray-and NMR-derived bead models suggest a role for side chain flexibility in protein hydrodynamics

N Rai, M Nöllmann, B Spotorno, G Tassara, O Byron… - Structure, 2005 - cell.com
Reduced numbers of frictional/scattering centers are essential for tractable hydrodynamic
and small-angle scattering data modeling. We present a method for generating medium …

Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X= Phe, Trp, Ser) on αIIbβ3 integrin conformation and oligomerization

RR Hantgan, C Paumi, M Rocco, JW Weisel - Biochemistry, 1999 - ACS Publications
The purpose of this investigation was to determine what structural changes convert “inert”
αIIbβ3 integrins into “activated” high-affinity receptors for adhesive proteins. Light scattering …

[PDF][PDF] Fibrinogen species as resolved by HPLC-SAXS data processing within the UltraScan Solution Modeler (US-SOMO) enhanced SAS module

E Brookes, J Pérez, B Cardinali, A Profumo… - Journal of applied …, 2013 - journals.iucr.org
Fibrinogen is a large heterogeneous aggregation/degradation-prone protein playing a
central role in blood coagulation and associated pathologies, whose structure is not …

[HTML][HTML] Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly

S Vijayakrishnan, SM Kelly, RJC Gilbert… - Journal of molecular …, 2010 - Elsevier
Mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly that is
responsible for glucose homeostasis maintenance and conversion of pyruvate into acetyl …