Searching for Conjugates as New Structures for Antifungal Therapies

I Muszalska-Kolos, PM Dwiecki - Journal of Medicinal Chemistry, 2024 - ACS Publications
The progressive increase in fungal infections and the decrease in the effectiveness of
current therapy explain research on new drugs. The synthesis of compounds with proven …

Anticancer and Antiphytopathogenic Activity of Fluorinated Isatins and Their Water-Soluble Hydrazone Derivatives

AV Bogdanov, M Neganova, A Voloshina… - International Journal of …, 2023 - mdpi.com
A series of new fluorinated 1-benzylisatins was synthesized in high yields via a simple one-
pot procedure in order to explore the possible effect of ortho-fluoro (3a), chloro (3b), or bis …

[HTML][HTML] Long-term antimicrobial effect of polylactide-based composites suitable for biomedical use

K Škrlová, Z Rybková, T Stachurová, J Zagora… - Polymer Testing, 2022 - Elsevier
This work deals with the preparation and characterization of antimicrobial polymeric
composite materials based on polylactide, which is currently widely investigated to produce …

Enhanced in vitro antibacterial effect against Enterococcus faecalis by using both low-dose cetylpyridinium chloride and silver ions

S Lv, W Fan, B Fan - BMC Oral Health, 2023 - Springer
Background Enterococcus faecalis (E. faecalis) is frequently isolated from root canals with
failed root canal treatments. Due to the strong ability of E. faecalis to resist many often-used …

Dual nanocarrier of chlorhexidine and fluconazole: Physicochemical characterization and effects on microcosm biofilms and oral keratinocytes

HC Araujo, JP Pessan, ACM Caldeirão, C Sampaio… - Journal of Dentistry, 2023 - Elsevier
Objectives This study assembled and characterized a dual nanocarrier of chlorhexidine
(CHX) and fluconazole (FLZ), and evaluated its antibiofilm and cytotoxic effects. Methods …

Nanocarriers of Miconazole or Fluconazole: Effects on Three-Species Candida Biofilms and Cytotoxic Effects In Vitro

ACM Caldeirão, HC Araujo, LS Arias… - Journal of fungi, 2021 - mdpi.com
The contribution of different Candida species in oral fungal infections has stimulated the
search for more effective therapies. This study assessed the antibiofilm effects of …

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection

N Akbar, R Siddiqui, M Khamis, T Ibrahim… - Experimental …, 2022 - Elsevier
Background Acanthamoeba keratitis is a painful, sight-threatening infection. It is commonly
associated with the use of contact lens. Several lines of evidence suggest inadequate …

Biocompatibility and biocidal effects of modified polylactide composites

T Stachurová, Z Rybková, K Škrlová… - Frontiers in …, 2022 - frontiersin.org
Polylactide (PLA) materials treated with antimicrobial fillers represent a suitable alternative
to the production of medical devices. Their advantage is that they can prevent the growth of …

Mechanisms of Triton X-100 reducing the Ag+-resistance of Enterococcus faecalis

S Lv, M Duan, B Fan, W Fan - World Journal of Microbiology and …, 2024 - Springer
To investigate the mechanism of Triton X-100 (TX-100) reducing the Ag+-resistance of
Enterococcus faecalis (E. faecalis), and evaluate the antibacterial effect of TX-100+ Ag+ …

Nanocarriers of antifungal drugs: possible strategies to overcome antimicrobial resistance

DR Monteiro, JP Pessan - Future Microbiology, 2022 - Taylor & Francis
Dysbiosis of the oral microbiome resulting from the selective multiplication of pathobiont
Candida can lead to oral candidiasis, an infectious condition of the soft tissues of the oral …