Peptidomimetics represent an important field in chemistry, pharmacology and material
science as they circumvent the limitations of traditional peptides used in therapy. Self …

Azapeptides are peptide analogs in which one or more of the amino residues is replaced by
a semicarbazide. This substitution of a nitrogen for the α-carbon center results in …

Conspectus Mimicry of bioactive conformations is critical for peptide-based medicinal
chemistry because such peptidomimetics may augment stability, enhance affinity, and …

A novel class of peptidomimetic foldamers based on diaza-peptide units are reported.
Circular dichroism, attenuated total reflection–Fourier transform infrared, NMR, and …

Heroin addiction is a wide-reaching problem with a spectrum of damaging social
consequences. A vaccine capable of blocking heroin's effects could provide a long-lasting …

Peptide‐based therapeutics have grown in importance over the last few decades.
Furthermore, peptides have been extensively used as lead compounds in the drug …

Covering: up to the end of 2015. Peptides are naturally occurring compounds that play an
important role in all living systems and are responsible for a range of essential functions …

Submonomer synthesis of aza-peptides featuring regioselective alkylation of peptide-bound
aza-Gly residues provided ten aza-analogues of the Growth Hormone Releasing Peptide-6 …

Transient soluble oligomers of amyloid-β (Aβ) are considered among the most toxic species
in Alzheimer's disease (AD). Soluble Aβ oligomers accumulate early prior to insoluble …

Aza-peptides are peptidomimetics in which one or more of the α-carbons, bearing the side-
chain residues, has been replaced by a nitrogen. These peptidomimetics have been shown …