Cancer metastasis is no longer viewed as a linear cascade of events but rather as a series
of concurrent, partially overlapping processes, as successfully metastasizing cells assume …

Most cancer patients do not die from the primary tumor but from its metastasis. Current in
vitro and in vivo cancer models are incapable of satisfactorily predicting the outcome of …

Highlights•C. elegans offers a powerful platform to emulate key aspects of human
pathology.•Focus on C. elegans models of the most common neurodegenerative …

Metal-based nanoparticles are widely used to deliver bioactive molecules and drugs to
improve cancer therapy. Several research works have highlighted the synthesis of gold and …

The nematode Caenorhabditis elegans was introduced as a model organism in biological
research by Sydney Brenner in the 1970s. Since then, it has been increasingly used for …

After decades of research, our knowledge of the complexity of cancer mechanisms,
elegantly summarized as 'hallmarks of cancer', is expanding, as are the therapeutic …

Caenorhabditis elegans (C. elegans) nematodes are a powerful model organism for diverse
biological and biomedical studies, benefiting from their genetic similarities to humans, small …

Tardigrades represent a phylum of very small aquatic animals in which many species have
evolved adaptations to survive under extreme environmental conditions, such as desiccation …

The clinical application of photodynamic therapy (PDT) is still limited because of the
drawbacks of the traditional photosensitizers, such as low singlet oxygen (1O2) quantum …

The discovery of the microRNAs, lin-4 and let-7 as critical mediators of normal development
in Caenorhabditis elegans and their conservation throughout evolution has spearheaded …