The perfluoroheteroaromatic reagent pentafluoropyridine has proved to be a highly reactive
electrophile, undergoing SNAr arylation reactions in the presence of a range of nucleophilic …

Over the past few decades, furopyridines have emerged as key structural subunits prevalent
in a number of natural products and structural analogues associated with interesting …

Reactions of 4-bromo-5-nitrophthalonitrile (BNPN) with enolates of alkyl 4-R-2, 4-
dioxobutanoates gave alkyl 3-acyl-5, 6-dicyanobenzofuran-2-carboxylates, 4-(2-R-2 …

Lithium–bromine exchange in 2-bromophenyl perfluoroaryl ethers or sulfides affords fused
fluorinated benzofurans or benzothiophenes respectively by SNAr substitution of the …

An expeditious multicomponent reaction to synthesize tetrasubstituted furo [2, 3-d] pyridazin-
4 (5 H)-ones is reported. In brief, hydrazonoyl chlorides react with isocyanoacetamides, in …

A concise strategy for the synthesis of 2, 3-substituted furo [2, 3-b] pyridines is described.
Mild, metal-free conditions were successfully applied to produce a range of 2-(alkyl or aryl)-3 …

Reaction of perfluoroquinoline 1 and perfluoroisoquinoline 2 with benzylamine gave mono-
and di-aminated quinoline and isoquinoline systems, respectively, depending upon the …

Site reactivity of some enolates derived from acetyl attached to the aromatic and
heteroaromatic system with pentafluoropyridine and 4-phenylsulfonyl-2, 3, 5, 6 …

Perfluoroheteroaromatic systems, such as pentafluoropyridine, tetrafluoropyrazine and
tetrafluoropyridazine, are highly electrophilic due to the presence of several fluorine atoms …

Some pentafluoropyridine derivatives have been synthesized by the reaction of
pentafluoropyridine with appropriate C, S and N-nucleophile such as malononitrile, 1-methyl …