Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update

M Mmatli, NM Mbelle, J Osei Sekyere - Frontiers in Cellular and …, 2022 - frontiersin.org
Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …

Updates on the global dissemination of colistin-resistant Escherichia coli: An emerging threat to public health

S Zhang, M Abbas, MU Rehman, M Wang, R Jia… - Science of the Total …, 2021 - Elsevier
Colistin drug resistance is an emerging public health threat worldwide. The adaptability,
existence and spread of colistin drug resistance in multiple reservoirs and ecological …

Mobile Colistin Resistance (mcr) Gene-Containing Organisms in Poultry Sector in Low- and Middle-Income Countries: Epidemiology, Characteristics, and One Health …

MU Anyanwu, IF Jaja, COR Okpala, EO Njoga… - Antibiotics, 2023 - mdpi.com
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that
threaten the clinical utility of colistin (COL), one of the highest-priority critically important …

mcr-Colistin Resistance Genes Mobilized by IncX4, IncHI2, and IncI2 Plasmids in Escherichia coli of Pigs and White Stork in Spain

L Migura-Garcia, JJ González-López… - Frontiers in …, 2020 - frontiersin.org
Colistin has become the last-line antimicrobial for the treatment of multidrug resistant (MDR)
Enterobacterales in human medicine. To date, several colistin resistance genes have been …

Detection of NDM-5 and MCR-1 antibiotic resistance encoding genes in Enterobacterales in long-distance migratory bird species Ciconia ciconia, Algeria

L Loucif, W Chelaghma, Z Cherak, E Bendjama… - Science of the Total …, 2022 - Elsevier
Abstract β-lactams and colistin resistance in Enterobacterales is a global public health issue.
In this study we aimed to investigate the occurrence and genetic determinants of Extended …

Wide Spread of blaCTX–M–9/mcr-9 IncHI2/ST1 Plasmids and CTX-M-9-Producing Escherichia coli and Enterobacter cloacae in Rescued Wild Animals

M Haenni, V Métayer, R Jarry, A Drapeau… - Frontiers in …, 2020 - frontiersin.org
Wildlife has recently been pinpointed as one of the drivers of dissemination of genes
conferring resistances to clinically important antimicrobials. The presence of both extended …

Epidemic HI2 Plasmids Mobilising the Carbapenemase Gene blaIMP-4 in Australian Clinical Samples Identified in Multiple Sublineages of Escherichia coli ST216 …

H Tarabai, ER Wyrsch, I Bitar, M Dolejska… - Microorganisms, 2021 - mdpi.com
Escherichia coli ST216, including those that carry bla KPC-2, bla FOX-5, bla CTX-M-15 and
mcr-1, have been linked to wild and urban-adapted birds and the colonisation of hospital …

High diversity of pathogenic Escherichia coli clones carrying mcr‐1 among gulls underlines the need for strategies at the environment–livestock–human interface

M Ribeiro‐Almeida, J Mourão, Â Novais… - Environmental …, 2022 - Wiley Online Library
The expansion of mcr‐carrying bacteria is a well‐recognized public health problem.
Measures to contain mcr spread have mainly been focused on the food–animal production …

Antibiotic-resistant bacteria in wildlife

M Dolejska - Antibiotic Resistance in the Environment: A Worldwide …, 2020 - Springer
The global dissemination of antibiotic-resistant bacteria (ARB) is one of the most important
issues for current medicine, having serious implications for public health. Particular concern …

Winged resistance: Storks and gulls increase carriage of antibiotic resistance by shifting from paddy fields to landfills

O Sacristán-Soriano, D Jarma, MI Sánchez… - Science of the Total …, 2024 - Elsevier
Waterbirds are vectors for the dissemination of antimicrobial resistance across
environments, with some species increasingly reliant on highly anthropized habitats for …