Natural and anthropogenic causes are continually growing sources of metals in the
ecosystem; hence, heavy metal (HM) accumulation has become a primary environmental …

Detection of toxic small molecule contaminants with sensitivity, accuracy, and specificity is a
challenging task. Traditionally used HPLC and mass spectrometry-based assays suffer from …

CRISPR-Cas systems have been widely used in genome editing and transcriptional
regulation. Recently, CRISPR-Cas effectors are adopted for biosensor construction due to its …

An aptamer is a single-stranded DNA or RNA that binds to a specific target with high binding
affinity. Aptamers are developed through the process of systematic evolution of ligands by …

Pesticide and mycotoxin residues in food are concerning as they are harmful to human
health. Traditional methods, such as high-performance liquid chromatography (HPLC) for …

Highlights•An aptamer with high affinity, high specificity, and high stability for binding to both
human-derived and rat-derived GDF15 was obtained.• The molecular mechanism and key …

Portable biosensors have emerged as powerful diagnostic tools for analyzing sensitive
biological samples. These biosensors offer sensitive detection capabilities by utilizing …

Small-molecule contaminants, such as antibiotics, pesticides, and plasticizers, have
emerged as one of the substances most detrimental to human health and the environment …

Analytical chemistry plays an irreplaceable role in the fields of energy, agriculture, medicine,
chemical industry, environmental protection, and so on. Thanks to the blooming prosperity of …

Redox reactions in live cells are generated by involving various redox biomolecules for
maintaining cell viability and functions. These qualities have been exploited in the …