Making proteomics data accessible and reusable: current state of proteomics databases and repositories

Y Perez‐Riverol, E Alpi, R Wang, H Hermjakob… - …, 2015 - Wiley Online Library
Compared to other data‐intensive disciplines such as genomics, public deposition and
storage of MS‐based proteomics, data are still less developed due to, among other reasons …

Proteomics and metabolomics approaches towards a functional insight onto AUTISM spectrum disorders: phenotype stratification and biomarker discovery

MV Ristori, SL Mortera, V Marzano, S Guerrera… - International journal of …, 2020 - mdpi.com
Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by
behavioral alterations and currently affect about 1% of children. Significant genetic factors …

The promise of multi-omics and clinical data integration to identify and target personalized healthcare approaches in autism spectrum disorders

R Higdon, RK Earl, L Stanberry, CM Hudac… - Omics: a journal of …, 2015 - liebertpub.com
Complex diseases are caused by a combination of genetic and environmental factors,
creating a difficult challenge for diagnosis and defining subtypes. This review article …

How Healthcare Can Refocus on Its Super-Customers (Patients, n =1) and Customers (Doctors and Nurses) by Leveraging Lessons from Amazon, Uber, and …

E Kolker, V Özdemir, E Kolker - Omics: a journal of integrative …, 2016 - liebertpub.com
Healthcare is transforming with data-intensive omics technologies and Big Data. The
“revolution” has already happened in technology, but the bottlenecks have shifted to the …

[HTML][HTML] Proteomics for systems toxicology

B Titz, A Elamin, F Martin, T Schneider, S Dijon… - Computational and …, 2014 - Elsevier
Current toxicology studies frequently lack measurements at molecular resolution to enable a
more mechanism-based and predictive toxicological assessment. Recently, a systems …

Inbreeding and selection shape genomic diversity in captive populations: Implications for the conservation of endangered species

JR Willoughby, JA Ivy, RC Lacy, JM Doyle… - PLoS …, 2017 - journals.plos.org
Captive breeding programs are often initiated to prevent species extinction until
reintroduction into the wild can occur. However, the evolution of captive populations via …

Toward more transparent and reproducible omics studies through a common metadata checklist and data publications

E Kolker, V Özdemir, L Martens, W Hancock… - Omics: a journal of …, 2014 - liebertpub.com
Biological processes are fundamentally driven by complex interactions between
biomolecules. Integrated high-throughput omics studies enable multifaceted views of cells …

MOPED 2.5—an integrated multi-omics resource: multi-omics profiling expression database now includes transcriptomics data

E Montague, L Stanberry, R Higdon, I Janko… - Omics: a journal of …, 2014 - liebertpub.com
Multi-omics data-driven scientific discovery crucially rests on high-throughput technologies
and data sharing. Currently, data are scattered across single omics repositories, stored in …

Proteomic discovery and development of a multiplexed targeted MRM-LC-MS/MS assay for urine biomarkers of extracellular matrix disruption in …

WE Heywood, S Camuzeaux, I Doykov… - Analytical …, 2015 - ACS Publications
The mucopolysaccharidoses (MPS) are lysosomal storage disorders that result from defects
in the catabolism of glycosaminoglycans. Impaired muscle, bone, and connective tissue are …

Azaspiracids increase mitochondrial dehydrogenases activity in hepatocytes: Involvement of potassium and chloride ions

M Pelin, J Kilcoyne, C Florio, P Hess, A Tubaro, S Sosa - Marine drugs, 2019 - mdpi.com
Background: Azaspiracids (AZAs) are marine toxins that are produced by Azadinium and
Amphidoma dinoflagellates that can contaminate edible shellfish inducing a foodborne …