The review focus on the use of lectin-based biosensors in the oncology field, and ponders
the potentialities of using these devices as analytical tools to monitor the levels of cancer …

The ovarian cancer biomarker CA125 has been extensively investigated over the last 30
years. The knowledge about the exact molecular nature of this protein, however, remains …

Lectins are carbohydrate recognizing proteins originating from diverse origins in nature,
including animals, plants, viruses, bacteria and fungus. Due to their exceptional glycan …

Ovarian cancer is the most lethal gynaecologic cancer affecting women. The most widely
used biomarker for ovarian cancer, CA125, lacks sensitivity and specificity. Here, we …

Protein glycosylation is one of the key processes that play essential roles in biological
functions and dysfunctions. However, progress in glycomics has considerably lagged …

Lectins act as effective diagnostic tools for screening potential cancer biomarkers because
of their ability to recognize the carbohydrate moiety of glycoproteins present in most complex …

CA125 is the most widely used tumour marker in ovarian cancer with unsatisfactory
sensitivity and specificity especially at early stage. It is quantified by antibody-based …

CA125 is a tumor antigen used to monitor the progression and regression of epithelial
ovarian cancer. Despite the widespread use of CA125, the biochemical and molecular …

In cancer treatment, non-invasive diagnosis can avoid complications of biopsy and other
unfavorable impacts on patient's health. DNA, methylation, SNPs, miRNA, mRNA, protein …

Abstract Mucin 16 (MUC16) is a transmembrane type mucin and its released extracellular
portion is designated as CA125 antigen. It is considered to be part of a supramolecular …