Background Theoretically, root resorption could be modulated by any medication taken that
exhibits possible effects on the implicated molecular pathways. Objectives To systematically …

Background As the taking of any medication may theoretically affect the complex pathways
responsible for periodontal tissue homeostasis and the events leading to orthodontic tooth …

Peripheral serotonin continuously reveals its unexpected involvements in many organ
functions. In bone tissue, there is an increasing evidence for a local serotonergic system …

Objective: To investigate the influence of lithium chloride (LiCl) on orthodontic tooth
movement (OTM), orthodontically induced root resorption (OIRR), and bone morphometry …

Introduction Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine adversely
affect bone mineral density (BMD) and turnover, thereby increasing the risk of fractures. The …

This study aimed to evaluate the effects of chronic use of fluoxetine on the amount of
orthodontic tooth movement and tissue changes in rats. A total of 192 Wistar rats were …

As any pharmaceutical substance may influence the events associated with orthodontic
tooth movement, it is of importance for the clinician to be able to recognize any prospective …

Background. Anchorage control is an essential part of orthodontic treatment planning,
especially in adult patients who demand a more convenient treatment. Zoledronic acid (ZA) …

Background. Orthodontic tooth movement (OTM) occurs in the alveolar bone; therefore, any
condition affecting bone quality can alter OTM. This study aimed to evaluate the effect of …

Objectives: Nitric oxide (NO) is a signaling molecule that mediates mechanical bone
loading. Cyclic guanosine 3′, 5′ monophosphate (cGMP) is a NO-induced effector …