[HTML][HTML] Polyoxovanadates with emerging biomedical activities

M Aureliano, NI Gumerova, G Sciortino… - Coordination Chemistry …, 2021 - Elsevier
Polyoxovanadates (POVs) are a subclass of a larger family of polyanionic group V and VI
metal-oxo clusters that are known as polyoxometalates (POMs). POMs have been found to …

Biological consequences of vanadium effects on formation of reactive oxygen species and lipid peroxidation

M Aureliano, AL De Sousa-Coelho, CC Dolan… - International Journal of …, 2023 - mdpi.com
Lipid peroxidation (LPO), a process that affects human health, can be induced by exposure
to vanadium salts and compounds. LPO is often exacerbated by oxidation stress, with some …

The antibacterial activity of polyoxometalates: structures, antibiotic effects and future perspectives

A Bijelic, M Aureliano, A Rompel - Chemical Communications, 2018 - pubs.rsc.org
Polyoxometalates (POMs) are, mostly anionic, metal oxide compounds that span a wide
range of tunable physical and chemical features rendering them very interesting for …

Polyoxometalates impact as anticancer agents

F Carvalho, M Aureliano - International journal of molecular sciences, 2023 - mdpi.com
Polyoxometalates (POMs) are oxoanions of transition metal ions, such as V, Mo, W, Nb, and
Pd, forming a variety of structures with a wide range of applications. Herein, we analyzed …

Hydrolysis, Ligand Exchange, and Redox Properties of Vanadium Compounds: Implications of Solution Transformation on Biological, Therapeutic, and Environmental …

R Dinda, E Garribba, D Sanna, DC Crans… - Chemical …, 2025 - ACS Publications
Vanadium is a transition metal with important industrial, technological, biological, and
biomedical applications widespread in the environment and in living beings. The different …

Vanadium and insulin: Partners in metabolic regulation

S Treviño, A Diaz - Journal of Inorganic Biochemistry, 2020 - Elsevier
Since the 1970s, the biological role of vanadium compounds has been discussed as insulin-
mimetic or insulin-enhancer agents. The action of vanadium compounds has been …

[HTML][HTML] Decavanadate and metformin-decavanadate effects in human melanoma cells

AL De Sousa-Coelho, M Aureliano, G Fraqueza… - Journal of Inorganic …, 2022 - Elsevier
Decavanadate is a polyoxometalate (POMs) that has shown extensive biological activities,
including antidiabetic and anticancer activity. Importantly, vanadium-based compounds as …

Biological properties of transition metal complexes with metformin and its analogues

DA Rusanov, J Zou, MV Babak - Pharmaceuticals, 2022 - mdpi.com
Metformin is a widely prescribed medication for the treatment and management of type 2
diabetes. It belongs to a class of biguanides, which are characterized by a wide range of …

Rationalizing the Decavanadate (V) and Oxidovanadium (IV) Binding to G-Actin and the Competition with Decaniobate (V) and ATP

G Sciortino, M Aureliano, E Garribba - Inorganic Chemistry, 2020 - ACS Publications
The experimental data collected over the past 15 years on the interaction of decavanadate
(V)(V10O286–; V10), a polyoxometalate (POM) with promising anticancer and antibacterial …

Repurposing therapeutic drugs complexed to vanadium in cancer

AL De Sousa-Coelho, G Fraqueza, M Aureliano - Pharmaceuticals, 2023 - mdpi.com
Repurposing drugs by uncovering new indications for approved drugs accelerates the
process of establishing new treatments and reduces the high costs of drug discovery and …