Gastric cancer accounts for the majority cancer-related deaths worldwide. Although various
methods have considerably improved the screening, diagnosis, and treatment of gastric …

Genetics and genomics in Peru: Clinical and research perspective - PMC Back to Top Skip to
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Background Stomach cancer mortality rates in South America are among the highest in the
world. In Peru, stomach cancer has the highest absolute number of cancer deaths in both …

It has been reported that IL-8 was involved in the promotion of invasion of Gastric Cancer
(GC), however the underlying mechanism by which IL-8 was observed to be able to promote …

Background The inflammatory response plays a key role at different stages of cancer
development. Allelic variants of the interleukin 1A (IL1A), interleukin 4 (IL4), nuclear factor …

There is overwhelming evidence that inflammation plays a key role in the pathogenesis of
cancer and its progression. Inflammation is regulated through a complex network of genes …

Background The roles of cyclooxygenase-2 (COX2)− 765G> C (rs20417) and− 1195G> A
(rs689466) polymorphisms in gastric cancer were intensively analyzed, but the results of …

Background: Solid neoplasms have a heterogeneous incidence worldwide and in Brazil.
Thus, the region delimited by the Legal Amazon has a distinct epidemiological profile. In …

The cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) pathway exerts deleterious
pleiotropic effects in inflammation-induced gastric carcinogenesis. We aimed to assess the …

AIM To perform a meta-analysis to investigate the association between cyclooxygenase-2
(COX-2)-1195G> A gene polymorphism and gastrointestinal cancers. METHODS …