Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …

Effective drug delivery and prevention of postoperative recurrence are significant challenges
for current glioblastoma (GBM) treatment. Poor drug delivery is mainly due to the presence …

Existing solid‐nanoparticle‐based drug delivery systems remain a great challenge for
glioblastoma chemotherapy due to their poor capacities in crossing the blood–brain …

Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …

The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …

Glioblastoma multiforme (GBM) treatment is hindered by complex pathologies and the need
to cross the blood–brain barrier (BBB) during drug delivery. Although exosomes have great …

Small‐interfering RNA (siRNA) therapy is considered a powerful therapeutic strategy for
treating cardiac hypertrophy, an important risk factor for subsequent cardiac morbidity and …

Pancreatic cancer is one of the deadly malignancies with a significant mortality rate and
there are currently few therapeutic options for it. The tumor microenvironment (TME) in …

Gliomas are the most aggressive and lethal tumors of the central nervous system, for which
few therapeutic options exist. Surgical resection is the primary treatment for most gliomas; …