[HTML][HTML] Functional neuroimaging in psychiatry and the case for failing better

MM Nour, Y Liu, RJ Dolan - Neuron, 2022 - cell.com
Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …

The future of brain circuit-targeted therapeutics

SH Siddiqi, S Khosravani, JD Rolston… - …, 2024 - nature.com
The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …

[HTML][HTML] The brain structure, immunometabolic and genetic mechanisms underlying the association between lifestyle and depression

Y Zhao, L Yang, BJ Sahakian, C Langley… - Nature Mental …, 2023 - nature.com
Lifestyle factors have been acknowledged to be modifiable targets that can be used to
counter the increasing prevalence of depression. This study aims to investigate combining …

Mapping lesion-related epilepsy to a human brain network

FL Schaper, J Nordberg, AL Cohen, C Lin, J Hsu… - JAMA …, 2023 - jamanetwork.com
Importance It remains unclear why lesions in some locations cause epilepsy while others do
not. Identifying the brain regions or networks associated with epilepsy by mapping these …

Lesion network mapping for symptom localization: recent developments and future directions

J Joutsa, MD Fox - Current opinion in neurology, 2022 - journals.lww.com
Lesion network mapping can be used to map lesion-induced symptoms to brain circuits
rather than single brain regions. Recent findings have provided insight into long-standing …

[HTML][HTML] Neural circuit selective for fast but not slow dopamine increases in drug reward

P Manza, D Tomasi, E Shokri-Kojori, R Zhang… - Nature …, 2023 - nature.com
The faster a drug enters the brain, the greater its addictive potential, yet the brain circuits
underlying the rate dependency to drug reward remain unresolved. With simultaneous PET …

[HTML][HTML] Association between vmPFC gray matter volume and smoking initiation in adolescents

S Xiang, T Jia, C Xie, W Cheng, B Chaarani… - Nature …, 2023 - nature.com
Smoking of cigarettes among young adolescents is a pressing public health issue. However,
the neural mechanisms underlying smoking initiation and sustenance during adolescence …

Network models to enhance the translational impact of cross-species studies

JK Brynildsen, K Rajan, MX Henderson… - Nature Reviews …, 2023 - nature.com
Neuroscience studies are often carried out in animal models for the purpose of
understanding specific aspects of the human condition. However, the translation of findings …

[HTML][HTML] Pathological fear, anxiety and negative affect exhibit distinct neurostructural signatures: evidence from psychiatric neuroimaging meta-analysis

X Liu, B Klugah-Brown, R Zhang, H Chen… - Translational …, 2022 - nature.com
Internalizing disorders encompass anxiety, fear and depressive disorders, which exhibit
overlap at both conceptual and symptom levels. Given that a neurobiological evaluation is …

Psychiatric sequelae of traumatic brain injury—future directions in research

LM Li, A Carson, K Dams-O'Connor - Nature Reviews Neurology, 2023 - nature.com
Despite growing appreciation that traumatic brain injury (TBI) is an important public health
burden, our understanding of the psychiatric and behavioural consequences of TBI remains …