Chitosan nanoparticles at the biological interface: implications for drug delivery

N Aibani, R Rai, P Patel, G Cuddihy, EK Wasan - Pharmaceutics, 2021 - mdpi.com
The unique properties of chitosan make it a useful choice for various nanoparticulate drug
delivery applications. Although chitosan is biocompatible and enables cellular uptake, its …

Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs

Y Lu, K Park - International journal of pharmaceutics, 2013 - Elsevier
Poorly soluble drugs often encounter low bioavailability and erratic absorption patterns in
the clinical setting. Due to the rising number of compounds having solubility issues, finding …

Redox-sensitive and hyaluronic acid functionalized liposomes for cytoplasmic drug delivery to osteosarcoma in animal models

Y Chi, X Yin, K Sun, S Feng, J Liu, D Chen… - Journal of Controlled …, 2017 - Elsevier
This study aimed to develop redox-sensitive and CD44-targeted liposomes to improve
chemotherapy of osteosarcoma. Cationic liposomes were prepared and stabilized with a …

Chitosan-based drug nanocarriers: where do we stand?

M Garcia-Fuentes, MJ Alonso - Journal of Controlled Release, 2012 - Elsevier
Chitosan-based nanocarriers have become one of the most intensively studied
transmucosal nanometric drug delivery platforms. This is due to a number of factors …

Advances in nano-delivery systems for doxorubicin: an updated insight

U Kanwal, N Irfan Bukhari, M Ovais, N Abass… - Journal of drug …, 2018 - Taylor & Francis
Doxorubicin (DOX) is the most effective chemotherapeutic drug developed against broad
range of cancers such as solid tumours, transplantable leukemias and lymphomas …

Multifaceted applications of chitosan in cancer drug delivery and therapy

A Babu, R Ramesh - Marine drugs, 2017 - mdpi.com
Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and
biodegradable nature of chitosan, it is intensively utilized in biomedical applications in …

A smart polysaccharide/drug conjugate for photodynamic therapy

SY Park, HJ Baik, YT Oh, KT Oh, YS Youn, ES Lee - Angewandte Chemie, 2011 - infona.pl
Trojanisches Pferd: Ein neu entwickeltes Polysaccharid‐Wirkstoff‐Konjugat (siehe Bild)
reagiert auf Änderungen des pH‐Werts und kann in HeLa‐Mäusetumoren eindringen, wie …

Nanomaterials as an advanced nano-tool for the doxorubicin delivery/Co-Delivery—A comprehensive review

R Arshad, MS Arshad, A Rahdar, D Hassan… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is the deadliest multifactorial disease, constituting variations at the molecular and
histological level. Cancer is being treated on advanced step via utilization of the multiple …

Pharmacokinetic studies of nanoparticles as a delivery system for conventional drugs and herb-derived compounds for cancer therapy: a systematic review

O Abdifetah, K Na-Bangchang - International journal of …, 2019 - Taylor & Francis
The poor pharmacokinetic characteristics of most anticancer drugs have limited their clinical
effectiveness. The application of nanoparticles as a novel drug delivery system has provided …

Recent advancement of chitosan-based nanoparticles for oral controlled delivery of insulin and other therapeutic agents

A Chaudhury, S Das - Aaps Pharmscitech, 2011 - Springer
Nanoparticles composed of naturally occurring biodegradable polymers have emerged as
potential carriers of various therapeutic agents for controlled drug delivery through the oral …