Gossypin: a flavonoid with diverse pharmacological effects

B Song, X Shen, C Tong, S Zhang… - Chemical Biology & …, 2023 - Wiley Online Library
Gossypin is a flavonoid compound prepared from chinese medicine Hibiscus, which not only
has significant pharmacological activities in antioxidant, anti‐inflammatory, neuroprotective …

Therapeutic benefits of gossypin as an emerging phytoconstituents of Hibiscus spp.: a critical review

G Jejurkar, M Chavan - Future Journal of Pharmaceutical Sciences, 2023 - Springer
Background Flavonoids are one of the crucial secondary metabolites as several functions
are carried out by flavonoids, including regulating cell growth, luring insects and pollinators …

Roles of flavonoids in ischemic heart disease: Cardioprotective effects and mechanisms against myocardial ischemia and reperfusion injury

H Xu, S Yu, C Lin, D Dong, J Xiao, Y Ye, M Wang - Phytomedicine, 2024 - Elsevier
Background Flavonoids are extensively present in fruits, vegetables, grains, and medicinal
plants. Myocardial ischemia and reperfusion (MI/R) comprise a sequence of detrimental …

Cardioprotective effect of gossypin against myocardial ischemic/reperfusion in rats via alteration of oxidative stress, inflammation and gut microbiota

G Cheng, J Zhang, S Jia, P Feng, F Chang… - Journal of …, 2022 - Taylor & Francis
Background Myocardial ischemic/reperfusion (I/R) injury is a key prognostic factor after the
myocardial infarction. However, at the time of reperfusion, the myocardial tissue has …

Vanillin and pentoxifylline ameliorate isoproterenol-induced myocardial injury in rats via the Akt/HIF-1α/VEGF signaling pathway

MM Elseweidy, SI Ali, MA Shaheen… - Food & Function, 2023 - pubs.rsc.org
Myocardial infarction (MI) is a major health problem associated with high morbidity and
mortality. Recently, angiogenesis has emerged as a novel therapeutic approach against …

Cardioprotective Effect of Flibanserin against Isoproterenol-Induced Myocardial Infarction in Female Rats: Role of Cardiac 5-HT2A Receptor Gene/5-HT/Ca2+ …

MI Ahmed, HMA Abdelrazek, YM Moustafa… - Pharmaceuticals, 2023 - mdpi.com
Myocardial infarction (MI) is a life-threatening ischemic disease and is one of the leading
causes of morbidity and mortality worldwide. Serotonin (5-HT) release during myocardial …

Anti-inflammatory, cardioprotective effect of gypenoside against isoproterenol-induced cardiac remodeling in rats via alteration of inflammation and gut microbiota

X Zhang, Y Zhao, X Zhao, J Zhang, J Diao, S Jia… - …, 2023 - Springer
Background Myocardial infarction (MI), commonly referred to as a heart attack, occurs when
the blood flow to a portion of the heart is blocked, causing damage to the heart muscle. In …

PEG-modified nano liposomes co-deliver Apigenin and RAGE-siRNA to protect myocardial ischemia injury

C Liu, X Zhang, H Yang, M Zhao, Y Liu, R Zhao… - International Journal of …, 2024 - Elsevier
Ischemic heart disease (IHD) is a cardiac disorder in which myocardial damage occurs as a
result of myocardial ischemia and hypoxia. Evidence suggests that oxidative stress and …

Unveiling the Cardioprotective Power: Liquid Chromatography–Mass Spectrometry (LC–MS)-Analyzed Neolamarckia cadamba (Roxb.) Bosser Leaf Ethanolic Extract …

RN Kumar, D Prasanth, PG Midthuri, SF Ahmad… - Plants, 2023 - mdpi.com
Neolamarckia cadamba (Roxb.) Bosser, a member of the Rubiaceae family, is a botanical
species with recognized therapeutic properties. It is commonly used in traditional medicine …

[HTML][HTML] A new target in inflammatory diseases: Lycopene

Z Karaköy, E Cadirci, B Dincer - The Eurasian Journal of Medicine, 2022 - ncbi.nlm.nih.gov
Inflammation is a response to various injuries, illnesses, and severe trauma. The primary
function of inflammation is to combat pathogens, eliminate them from the body, and initiate …