Beta2-adrenergic agonists (β2-agonists) play a pivotal role in the acute and chronic
management of asthma. Their major action on the airways is the relaxation of smooth …

Rational Doxofylline is a xanthine drug that has been used as a treatment for respiratory
diseases for more than 30 years. In addition to doxofylline being a bronchodilator, some …

We have reported that CD54 on eosinophils is involved in eosinophil degranulation.
However, the role of CD54 in eosinophil and neutrophil superoxide production is still …

Background: Bronchial asthma is characterized by infiltration of eosinophils and other
inflammatory cells into the airways. Binding to adhesion molecules expressed on …

Background: Increasing evidence regarding asthma suggests that CD4+ cells are
preferentially recruited to sites of bronchial inflammation. Interleukin (IL)-16 has been …

Background: Viral respiratory tract infections play an important role in the inception and
exacerbation of asthma. Eosinophils, major effector cells in asthma, often accumulate in the …

Inhibiting the release of toxic granule proteins from eosinophils is a possible means of
treating allergic inflammation. This study was performed to examine whether procaterol and …

Angiotensin (Ang‐II) is a key molecule in the development of cardiac ischaemic disorders
and displays proinflammatory activity in vivo. Since intracellular cyclic nucleotides elevating …

Background: Recent evidence suggests that both neutrophilic and eosinophilic inflammation
persist in the airways of patients with severe asthma. Neutrophils can secrete a variety of …

Background: Although procaterol is used clinically as a β 2-adrenergic receptor agonist to
relax airway smooth muscle, it has not yet been clarified whether procaterol has inotropic …