Resistant hypertension: detection, evaluation, and management: a scientific statement from the American Heart Association

RM Carey, DA Calhoun, GL Bakris, RD Brook… - …, 2018 - Am Heart Assoc
Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a
patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a …

The sympathetic nervous system alterations in human hypertension

G Grassi, A Mark, M Esler - Circulation research, 2015 - Am Heart Assoc
Several articles have dealt with the importance and mechanisms of the sympathetic nervous
system alterations in experimental animal models of hypertension. This review addresses …

Methods and systems for thermally-induced renal neuromodulation

A Wu, BJ Clark, E Thai, N Zadno, D Zarins - US Patent 9,345,900, 2016 - Google Patents
Methods and system are provided for thermally-induced renal neuromodulation. Thermally-
induced renal neuromodulation may be achieved via direct and/or via indirect application of …

Expert consensus document from the European Society of Cardiology on catheter-based renal denervation

F Mahfoud, TF Lüscher, B Andersson… - European Heart …, 2013 - academic.oup.com
Hypertension is highly prevalent and one of the most frequent chronic diseases worldwide. 1
It has been suggested that over the next two decades up to 50% of the adult population will …

Ultrasound apparatuses for thermally-induced renal neuromodulation

D Demarais, N Zadno, BJ Clark, E Thai… - US Patent …, 2014 - Google Patents
Aug. 16, 2007, noW Pat. No. 7,717,948, Which is a(Continued) continuation of application
No. 11/504,117,? led on continuatlon-m-part of apphcation No. 10/408,665,? led on Apr. 8 …

Effectiveness of renal denervation therapy for resistant hypertension: a systematic review and meta-analysis

MI Davis, KB Filion, D Zhang, MJ Eisenberg… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to determine the current effectiveness and safety of
sympathetic renal denervation (RDN) for resistant hypertension. Background: RDN is a …

Methods and apparatus for intravasculary-induced neuromodulation

D Demarais, H Gifford III, M Deem, D Sutton… - US Patent …, 2014 - Google Patents
Methods and apparatus are provided for intravascularly-in duced neuromodulation or
denervation. Neuromodulation may be achieved via direct and/or via indirect application of …

Methods for monitoring renal neuromodulation

M Deem, H Gifford III, D Demarais, D Sutton… - US Patent …, 2014 - Google Patents
Methods and apparatus are provided for renal neuromodulation using a pulsed electric field
to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (eg …

Devices, systems and methods for evaluation and feedback of neuromodulation treatment

S Ballakur, R Beetel, P Friedrichs, A Wu… - US Patent …, 2015 - Google Patents
(60) Provisional application No. 61/406.531, filed on Oct. 25, 2010, provisional application
No. 61/528,108, Primary Examiner—Amanda Patton filed on Aug. 26, 2011, provisional …

Apparatuses for thermally-induced renal neuromodulation

D Demarais, N Zadno, BJ Clark, E Thai… - US Patent …, 2015 - Google Patents
Methods and apparatus are provided for thermally-induced renal neuromodulation.
Thermally-induced renal neuro modulation may be achieved via direct and/or via indirect …