G protein Gβγ subunits are key mediators of G protein-coupled receptor (GPCR) signaling
under physiological and pathological conditions; their inhibitors have been tested for the …

G protein-coupled receptors (GPCRs) are plasma membrane proteins associated with an
array of functions. Mutations in these receptors lead to a number of genetic diseases …

Estrogen excess in females has been linked to a diverse array of chronic and acute
diseases. Emerging research shows that exposure to estrogen-like compounds such as …

This narrative review is concerned with genetic variants of the genes encoding
gonadotrophin subunits and their receptors, as well as their implications into the diagnosis …

Misfolding of G protein-coupled receptors (GPCRs) caused by mutations frequently leads to
disease due to intracellular trapping of the conformationally abnormal receptor. Several …

The approaches to correct thyroid deficiency include replacement therapy with thyroid
hormones (THs), but such therapy causes a number of side effects. A possible alternative is …

G protein‐coupled receptors (GPCRs) are central to the functioning of the hypothalamic–
pituitary–gonadal axis (HPG axis) and include the rhodopsin‐like GPCR family members …

G protein-coupled receptors (GPCRs) facilitate the majority of signal transductions across
cell membranes in humans, with numerous diseases attributed to inactivating GPCR …

Kisspeptin (KISS1) and its cognate receptor (KISS1R) are implicated in the progression of
various cancers. A gallium‐68 labelled kisspeptin‐10 (KP10), the minimal biologically active …

Adequate protein folding and trafficking represent crucial processes in the proper
functioning of cells. Their integrity is ensured by highly regulated multistep quality control …