S100 is a multigenic family of non-ubiquitous Ca2+-modulated proteins of the EF-hand type
expressed in vertebrates exclusively and implicated in intracellular and extracellular …

S100B is a calcium‐binding peptide produced mainly by astrocytes that exert paracrine and
autocrine effects on neurons and glia. Some knowledge has been acquired from in vitro and …

The Receptor for Advanced Glycation Endproducts (RAGE) is a multi-ligand receptor of the
immunoglobulin family. RAGE interacts with structurally different ligands probably through …

A multigenic family of Ca2+-binding proteins of the EF-hand type known as S100 comprises
19 members that are differentially expressed in a large number of cell types. Members of this …

The calcium binding proteins of the EF-hand super-family are involved in the regulation of all
aspects of cell function. These proteins exhibit a great diversity of composition, structure …

This Handbook on Metalloproteins focuses on the available structural information of proteins
and their metal ion coordination spheres. It centers on the metal ions indispensable for life …

The EF‐hand motif, which assumes a helix‐loop‐helix structure normally responsible for
Ca2+ binding, is found in a large number of functionally diverse Ca2+ binding proteins …

The aggregation and membrane fusion properties of annexin II are modulated by the
association with a regulatory light chain called p11. p11 is a member of the S100 EF-hand …

Nervous system development and plasticity require regulation of cell proliferation, survival,
neurite outgrowth and synapse formation by specific extracellular factors. The EF‐hand …

Abstract S100 proteins (16 members) show a very divergent pattern of cell-and tissue-
specific expression, of subcel-lular localizations and relocations, of post-translational …