[HTML][HTML] Pathogenesis of hepatitis B virus infection

TF Baumert, R Thimme… - World journal of …, 2007 - ncbi.nlm.nih.gov
Infection with hepatitis B virus (HBV) leads to a wide spectrum of clinical presentations
ranging from an asymptomatic carrier state to self-limited acute or fulminant hepatitis to …

HBsAg variants: diagnostic-escape and diagnostic dilemma

SM Alavian, WF Carman, SM Jazayeri - Journal of Clinical virology, 2013 - Elsevier
A wide variety of commercial assays is available for the detection of hepatitis B surface
antigen (HBsAg). Clearly, the sensitivity of an assay to detect a variant is dependent on the …

Coexistence of hepatitis B surface antigen (HBs Ag) and anti-HBs antibodies in chronic hepatitis B virus carriers: influence of “a” determinant variants

O Lada, Y Benhamou, T Poynard, V Thibault - Journal of virology, 2006 - Am Soc Microbiol
In chronic hepatitis B (CHB), the persistence of hepatitis B surface antigen (HBs Ag) is
sometimes associated with antibodies (Ab) to HBs (anti-HBs). To assess the hypothesis of …

N-glycosylation mutations within hepatitis B virus surface major hydrophilic region contribute mostly to immune escape

DM Yu, XH Li, V Mom, ZH Lu, XW Liao, Y Han… - Journal of …, 2014 - Elsevier
Background & Aims HBV immune escape represents a challenge to prevention, diagnosis,
and treatment of hepatitis B. Here, we analyzed the molecular and clinical characteristics of …

Increased seroprevalence of HBV DNA with mutations in the s gene among individuals greater than 18 years old after complete vaccination

MW Lai, TY Lin, KC Tsao, CG Huang, MJ Hsiao… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Despite the success of a universal vaccination program against
hepatitis B virus (HBV) in Taiwan, a small but substantial proportion of individuals remain …

The potential of 1018 ISS adjuvant in hepatitis B vaccines: HEPLISAV™ review

NF Eng, N Bhardwaj, R Mulligan… - Human vaccines & …, 2013 - Taylor & Francis
Hepatitis B (HBV) virus infects the liver, and upon chronic infection, can cause liver cirrhosis
and hepatocellular carcinoma. Despite universal vaccination programs against the virus …

Atypical serological profiles in hepatitis B virus infection

RAA Pondé - European journal of clinical microbiology & infectious …, 2013 - Springer
During hepatitis B virus (HBV) infection, at least four antigen–antibody systems are
observed: HBsAg and anti-HBs; preS antigen and anti-preS antibody; HBcAg and anti-HBc; …

Immune control of hepatitis B virus

T Bauer, M Sprinzl, U Protzer - Digestive Diseases, 2011 - karger.com
Human hepatitis B virus (HBV) infects the liver of humans or humanoid primates. In humans,
HBV infection often causes an inflammatory liver disease–hepatitis B. The virus is …

Naturally occurring hepatitis B virus B‐cell and T‐cell epitope mutants in hepatitis B vaccinated children

YM Lin, GM Jow, SC Mu… - The Scientific World …, 2013 - Wiley Online Library
To control hepatitis B virus (HBV) infection, a universal HBV vaccination program for infants
was launched in Taiwan in 1984. The aim of this study was to investigate the role of B‐cell …

Epidemiological characteristics of the carriers with coexistence of HB sAg and anti‐HB s based on a community cohort study

Z Pu, D Li, A Wang, H Su, Z Shao, J Zhang… - Journal of viral …, 2016 - Wiley Online Library
The coexistence of HB sAg and anti‐HB s is an atypical serological pattern in HBV infection.
There is no epidemiological characteristics of this serological pattern in the community and …