Neuromodulation by the immune system: a focus on cytokines
Interactions between the immune system and the nervous system have been described
mostly in the context of diseases. More recent studies have begun to reveal how certain …
mostly in the context of diseases. More recent studies have begun to reveal how certain …
An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges
The CNS is ensheathed by the meninges and cerebrospinal fluid, and recent findings
suggest that these CNS-associated border tissues have complex immunological functions …
suggest that these CNS-associated border tissues have complex immunological functions …
Myeloid cells in the central nervous system
The central nervous system (CNS) and its meningeal coverings accommodate a diverse
myeloid compartment that includes parenchymal microglia and perivascular macrophages …
myeloid compartment that includes parenchymal microglia and perivascular macrophages …
Advances in meningeal immunity
R Rua, DB McGavern - Trends in molecular medicine, 2018 - cell.com
The central nervous system (CNS) is an immunologically specialized tissue protected by a
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …
Role of SARS-CoV-2 spike-protein-induced activation of microglia and mast cells in the pathogenesis of neuro-COVID
TC Theoharides, D Kempuraj - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
Innate immunity in the central nervous system
RM Ransohoff, MA Brown - The Journal of clinical …, 2012 - Am Soc Clin Investig
Immune responses in the CNS are common, despite its perception as a site of immune
privilege. These responses can be mediated by resident microglia and astrocytes, which are …
privilege. These responses can be mediated by resident microglia and astrocytes, which are …
Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey
BB Aggarwal, SC Gupta, JH Kim - Blood, The Journal of the …, 2012 - ashpublications.org
Although activity that induced tumor regression was observed and termed tumor necrosis
factor (TNF) as early as the 1960s, the true identity of TNF was not clear until 1984, when …
factor (TNF) as early as the 1960s, the true identity of TNF was not clear until 1984, when …
[HTML][HTML] Mast cells and inflammation
Mast cells are well known for their role in allergic and anaphylactic reactions, as well as their
involvement in acquired and innate immunity. Increasing evidence now implicates mast cells …
involvement in acquired and innate immunity. Increasing evidence now implicates mast cells …
Inflammatory disequilibrium in stroke
D Petrovic-Djergovic, SN Goonewardena… - Circulation …, 2016 - Am Heart Assoc
Over the past several decades, there have been substantial advances in our knowledge of
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …