Dynamics of ACTH and cortisol secretion and implications for disease

SL Lightman, MT Birnie… - Endocrine …, 2020 - academic.oup.com
The past decade has seen several critical advances in our understanding of hypothalamic–
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …

Stress, glucocorticoids and memory: implications for treating fear-related disorders

D de Quervain, L Schwabe… - Nature Reviews …, 2017 - nature.com
Glucocorticoid stress hormones are crucially involved in modulating mnemonic processing
of emotionally arousing experiences. They enhance the consolidation of new memories …

Acute stress and episodic memory retrieval: neurobiological mechanisms and behavioral consequences

SA Gagnon, AD Wagner - Annals of the New York Academy of …, 2016 - Wiley Online Library
Episodic retrieval allows people to access memories from the past to guide current thoughts
and decisions. In many real‐world situations, retrieval occurs under conditions of acute …

Stress and memory in humans: twelve years of progress?

OT Wolf - Brain research, 2009 - Elsevier
Stress leads to an enhanced activity of the hypothalamus–pituitary adrenal (HPA) axis
resulting in an increased release of glucocorticoids from the adrenal cortex. These …

Glucocorticoids and the regulation of memory in health and disease

JF Dominique, A Aerni, G Schelling… - Frontiers in …, 2009 - Elsevier
Over the last decades considerable evidence has accumulated indicating that
glucocorticoids–stress hormones released from the adrenal cortex–are crucially involved in …

Stress hormone regulation: biological role and translation into therapy

F Holsboer, M Ising - Annual review of psychology, 2010 - annualreviews.org
Stress is defined as a state of perturbed homeostasis following endangerment that evokes
manifold adaptive reactions, which are summarized as the stress response. In the case of …

Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects

LL Judd, PJ Schettler, ES Brown… - American Journal of …, 2014 - Am Psychiatric Assoc
Glucocorticoids are the most commonly prescribed anti-inflammatory/immunosuppressant
medications worldwide. This article highlights the risk of clinically significant and sometimes …

Long-term fatigue and cognitive disorders in breast cancer survivors

F Joly, M Lange, M Dos Santos, I Vaz-Luis, A Di Meglio - Cancers, 2019 - mdpi.com
Survivors of early-stage breast cancer may report treatment-related side effects that persist
for several years after the end of primary treatment. Among these, fatigue and cognitive …

Corticosteroid-related central nervous system side effects

M Ciriaco, P Ventrice, G Russo… - Journal of …, 2013 - journals.sagepub.com
Corticosteroids have been used since the 50s as anti-inflammatory and immunosuppressive
drugs for the treatment of several pathologies such as asthma, allergy, rheumatoid arthritis …

Circadian regulation of hippocampal function is disrupted with corticosteroid treatment

MT Birnie, MDB Claydon, O Troy… - Proceedings of the …, 2023 - National Acad Sciences
Disrupted circadian activity is associated with many neuropsychiatric disorders. A major
coordinator of circadian biological systems is adrenal glucocorticoid secretion which exhibits …