'Liking'and 'wanting'in eating and food reward: Brain mechanisms and clinical implications

I Morales, KC Berridge - Physiology & behavior, 2020 - Elsevier
It is becoming clearer how neurobiological mechanisms generate 'liking'and
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …

Significance of the insula for the evolution of human awareness of feelings from the body

AD Craig - Annals of the new York Academy of Sciences, 2011 - Wiley Online Library
An ascending sensory pathway that underlies feelings from the body, such as cooling or
toothache, terminates in the posterior insula. Considerable evidence suggests that this …

The theory of constructed emotion: an active inference account of interoception and categorization

LF Barrett - Social cognitive and affective neuroscience, 2017 - academic.oup.com
The science of emotion has been using folk psychology categories derived from philosophy
to search for the brain basis of emotion. The last two decades of neuroscience research …

Persistence of feelings and sentience after bilateral damage of the insula

A Damasio, H Damasio, D Tranel - Cerebral cortex, 2013 - academic.oup.com
It has been convincingly established, over the past decade, that the human insular cortices
are involved in processing both body feelings (such as pain) and feelings of emotion …

The pathways of interoceptive awareness

SS Khalsa, D Rudrauf, JS Feinstein, D Tranel - Nature neuroscience, 2009 - nature.com
A network of cortical brain regions, including the insula and anterior cingulate cortex (ACC),
has been proposed as the critical and sole substrate for interoceptive awareness …

Opioid and orexin hedonic hotspots in rat orbitofrontal cortex and insula

DC Castro, KC Berridge - Proceedings of the National …, 2017 - National Acad Sciences
Hedonic hotspots are brain sites where particular neurochemical stimulations causally
amplify the hedonic impact of sensory rewards, such as “liking” for sweetness. Here, we …

Amylin-Calcitonin receptor signaling in the medial preoptic area mediates affiliative social behaviors in female mice

K Fukumitsu, M Kaneko, T Maruyama… - Nature …, 2022 - nature.com
Social animals actively engage in contact with conspecifics and experience stress upon
isolation. However, the neural mechanisms coordinating the sensing and seeking of social …

A review of behavioral methods for the evaluation of cognitive performance in animal models: current techniques and links to human cognition

M Ghafarimoghadam, R Mashayekh, M Gholami… - Physiology & …, 2022 - Elsevier
Introduction: Memory is defined as the ability to store, maintain and retrieve information.
Learning is the acquisition of information that changes behavior and memory. Stress …

Preserved self-awareness following extensive bilateral brain damage to the insula, anterior cingulate, and medial prefrontal cortices

CL Philippi, JS Feinstein, SS Khalsa, A Damasio… - 2012 - journals.plos.org
It has been proposed that self-awareness (SA), a multifaceted phenomenon central to
human consciousness, depends critically on specific brain regions, namely the insular …

The necessity of the hippocampus for statistical learning

NV Covington, S Brown-Schmidt… - Journal of cognitive …, 2018 - direct.mit.edu
Converging evidence points to a role for the hippocampus in statistical learning, but open
questions about its necessity remain. Evidence for necessity comes from Schapiro and …