Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration

RL Schnaar, R Gerardy-Schahn… - Physiological …, 2014 - journals.physiology.org
Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

Cell and molecular mechanisms involved in the migration of cortical interneurons

C Métin, JP Baudoin, S Rakić… - European Journal of …, 2006 - Wiley Online Library
Since the discovery that the vast majority of the GABA‐containing interneurons of the
cerebral cortex arise in the subpallium, considerable effort has been put into the description …

[HTML][HTML] Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

O Peñagarikano, BS Abrahams, EI Herman… - Cell, 2011 - cell.com
Although many genes predisposing to autism spectrum disorders (ASD) have been
identified, the biological mechanism (s) remain unclear. Mouse models based on human …

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

PH Kuhn, AV Colombo, B Schusser, D Dreymueller… - Elife, 2016 - elifesciences.org
Metzincin metalloproteases have major roles in intercellular communication by modulating
the function of membrane proteins. One of the proteases is the a-disintegrin-and …

Pioneering axons regulate neuronal polarization in the developing cerebral cortex

T Namba, Y Kibe, Y Funahashi, S Nakamuta, T Takano… - Neuron, 2014 - cell.com
The polarization of neurons, which mainly includes the differentiation of axons and
dendrites, is regulated by cell-autonomous and non-cell-autonomous factors. In the …

Contactins: emerging key roles in the development and function of the nervous system

Y Shimoda, K Watanabe - Cell adhesion & migration, 2009 - Taylor & Francis
Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that
are expressed exclusively in the nervous system. The subgroup consists of six members …

BIG-2 mediates olfactory axon convergence to target glomeruli

T Kaneko-Goto, S Yoshihara, H Miyazaki, Y Yoshihara - Neuron, 2008 - cell.com
Olfactory sensory neurons expressing a given odorant receptor converge axons onto a few
topographically fixed glomeruli in the olfactory bulb, leading to establishment of the odor …

Neuronal migration disorders: focus on the cytoskeleton and epilepsy

MA Stouffer, JA Golden, F Francis - Neurobiology of disease, 2016 - Elsevier
A wide spectrum of focal, regional, or diffuse structural brain abnormalities, collectively
known as malformations of cortical development (MCDs), frequently manifest with …

Production and organization of neocortical interneurons

KT Sultan, KN Brown, SH Shi - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Inhibitory GABA (γ-aminobutyric acid)-ergic interneurons are a vital component of the
neocortex responsible for shaping its output through a variety of inhibitions. Consisting of …

The potential role of proinflammatory and antiinflammatory cytokines in Alzheimer disease pathogenesis

G Azizi, A Mirshafiey - Immunopharmacology and …, 2012 - Taylor & Francis
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by destructive
alterations of neurons (neurofibrillary tangles and amyloid plaques), and cognitive …