Translational considerations in injectable cell-based therapeutics for neurological applications: concepts, progress and challenges
Significant progress has been made during the past decade towards the clinical adoption of
cell-based therapeutics. However, existing cell-delivery approaches have shown limited …
cell-based therapeutics. However, existing cell-delivery approaches have shown limited …
Bioscaffold-induced brain tissue regeneration
M Modo - Frontiers in Neuroscience, 2019 - frontiersin.org
Brain tissue lost after a stroke is not regenerated, although a repair response associated
with neurogenesis does occur. A failure to regenerate functional brain tissue is not caused …
with neurogenesis does occur. A failure to regenerate functional brain tissue is not caused …
Stroke recovery and rehabilitation in 2016: a year in review of basic science and clinical science
H Zheng, N Cao, Y Yin, W Feng - Stroke and Vascular Neurology, 2017 - svn.bmj.com
We manually searched professional journals with an average 5-year impact factor> 3 (from
2012 to 2016) that were known to publish manuscript with topics in stroke recovery and …
2012 to 2016) that were known to publish manuscript with topics in stroke recovery and …
ECM hydrogel improves the delivery of PEG microsphere-encapsulated neural stem cells and endothelial cells into tissue cavities caused by stroke
H Ghuman, R Matta, A Tompkins, F Nitzsche… - Brain research …, 2021 - Elsevier
Intracerebral implantation of neural stem cells (NSCs) to treat stroke remains an inefficient
process with< 5% of injected cells being retained. To improve the retention and distribution …
process with< 5% of injected cells being retained. To improve the retention and distribution …
Eight-Coordinate, Stable Fe(II) Complex as a Dual 19F and CEST Contrast Agent for Ratiometric pH Imaging
Accurate mapping of small changes in pH is essential to the diagnosis of diseases such as
cancer. The difficulty in mapping pH accurately in vivo resides in the need for the probe to …
cancer. The difficulty in mapping pH accurately in vivo resides in the need for the probe to …
A roadmap for promoting endogenous in situ tissue restoration using inductive bioscaffolds after acute brain injury
M Modo, SF Badylak - Brain research bulletin, 2019 - Elsevier
The regeneration of brain tissue remains one of the greatest unsolved challenges in
medicine and by many is considered unfeasible. Indeed, the adult mammalian brain does …
medicine and by many is considered unfeasible. Indeed, the adult mammalian brain does …
Advances in monitoring cell-based therapies with magnetic resonance imaging: future perspectives
Cell-based therapies are currently being developed for applications in both regenerative
medicine and in oncology. Preclinical, translational, and clinical research on cell-based …
medicine and in oncology. Preclinical, translational, and clinical research on cell-based …
CEST‐MRI for glioma pH quantification in mouse model: Validation by immunohistochemistry
In glioma, the acidification of the extracellular tumor microenvironment drives proliferation,
angiogenesis, immunosuppression, invasion and chemoresistance. Therefore …
angiogenesis, immunosuppression, invasion and chemoresistance. Therefore …
Inorganic nanoparticles for X-ray computed tomography imaging
In the last two decades, nanoparticle contrast agents have emerged as an essential tool for
preclinical imaging and diagnosis. Besides their main advantage, related to their size range …
preclinical imaging and diagnosis. Besides their main advantage, related to their size range …
MRI and fluorescence studies of Saccharomyces cerevisiae loaded with a bimodal Fe (III) T1 contrast agent
Labeling of cells with paramagnetic metal complexes produces changes in MRI properties
that have applications in cell tracking and identification. Here we show that fungi, specifically …
that have applications in cell tracking and identification. Here we show that fungi, specifically …