In this study, an efficient synthesis of new thiazole-pyrazoline hybrids was investigated and
hybrids were screened for their antimicrobial activities against four species of pathogenic …

A series of various substituted thiazole-pyrazole hybrids 5, 7, 8, and 9 were synthesized, and
their chemical structures were confirmed by spectral data (infrared, 1 H & 13 C NMR and …

Abstract Context [3+ 2] cycloaddition processes between isoalantolactone (ISALL) and
diazocyclopropane (DCYP), have been surveyed exercising the MEDT, reactivity indices …

Herein, we report a sustainable, atom and step-efficient protocol for the one-pot preparation
of azido and triazole-functionalized pyrazoline employing a non-toxic, biodegradable, and …

Abstract Fused pyrazoles and 2, 5-disubstituted thiazolinone derivatives are attractive
molecules for drug design development that are widely recognized as significant biological …

The present work describes the unrevealed potential of tetrahydropyridines as anticancer
and anti-tubercular agents along with DFT, ADMET, drug-likeliness and molecular docking …

Designing innovative one-pot reactions using eco-friendly methodologies has attracted a lot
of attention in drug development, organic synthesis, and material sciences due to the …

En química medicinal, se dirigen continuamente extensos esfuerzos en investigación al
descubrimiento de nuevos heterociclos con efectos farmacológicos apropiados …

In the title compound, C22H22N2O4, the central pyrazoline ring exhibits a nearly planar
structure (rms deviation= 0.025 Å) despite having two sp3 carbon atoms. The pyrazoline ring …

Abstract The [3+ 2]-cycloaddition of α, β-unsaturated ketones with hydrazonoyl chloride-
derived nitrile imines was efficiently performed using Na2CO3 as a base affording …