Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover,
the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities …

Ferulic acid is being screened in preclinical settings to combat various neurological
disorders. It is a naturally occurring dietary flavonoid commonly found in grains, fruits, and …

Cerebrovascular disease and its risk factors cause persistent decrease of cerebral blood
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …

Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

Objective Role of apoptosis and neuroinflammation have been well established in the
pathogenesis of epilepsy. It has been reported that the activation of nuclear factor-erythroid …

Background Ferroptosis, a novel manner of cell death depended on iron ion, contributed to
goat mammary epithelial cell dysfunction. Interleukin-6 (IL-6) is a major pro-inflammatory …

Background Available anti-seizure medications (ASMs) target the symptomatology of the
disease rather than any significant disease/epileptogenesis modifying actions. There are …

Metformin, a widely prescribed medication for type 2 diabetes, has garnered increasing
attention for its potential neuroprotective properties due to the growing demand for …

The transcriptional regulator nuclear factor kappa B (NF-κB) modulates cellular biological
activity by binding to promoter regions in the nucleus and transcribing various protein …

Epilepsy is a neurological disorder characterized by an enduring predisposition to generate
and aggravate epileptic seizures affecting around 1% of global population making it a …