Early life microbial exposures and allergy risks: opportunities for prevention

H Renz, C Skevaki - Nature Reviews Immunology, 2021 - nature.com
Allergies, including asthma, food allergy and atopic dermatitis, are increasing in prevalence,
particularly in westernized countries. Although a detailed mechanistic explanation for this …

[HTML][HTML] Torquetenovirus: the human virome from bench to bedside

D Focosi, G Antonelli, M Pistello, F Maggi - Clinical Microbiology and …, 2016 - Elsevier
Torquetenovirus (TTV) is the most abundant component of human virome. Virologists have
long ignored this orphan and highly divergent virus, in part because TTV cannot be cultured …

Human anelloviruses: diverse, omnipresent and commensal members of the virome

J Kaczorowska, L Van Der Hoek - FEMS Microbiology Reviews, 2020 - academic.oup.com
Anelloviruses are small, single stranded circular DNA viruses. They are extremely diverse
and have not been associated with any disease so far. Strikingly, these small entities infect …

Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

[HTML][HTML] Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients—a prospective observational trial

K Doberer, M Schiemann, R Strassl… - American Journal of …, 2020 - Elsevier
The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

[HTML][HTML] Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

O Rezahosseini, CH Drabe, SS Sørensen… - Transplantation …, 2019 - Elsevier
Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid
rejection of the transplanted organ. Immunosuppressive therapy increases the risk of …

The virome and its major component, anellovirus, a convoluted system molding human immune defenses and possibly affecting the development of asthma and …

G Freer, F Maggi, M Pifferi, ME Di Cicco… - Frontiers in …, 2018 - frontiersin.org
The microbiome, a thriving and complex microbial community colonizing the human body,
has a broad impact on human health. Colonization is a continuous process that starts very …

Factors that may impact on immunosenescence: an appraisal

J Ongrádi, V Kövesdi - Immunity & ageing, 2010 - Springer
The increasing ratio of ageing population poses new challenges to healthcare systems. The
elderly frequently suffer from severe infections. Vaccination could protect them against …

Early post-transplant torquetenovirus viremia predicts cytomegalovirus reactivations in solid organ transplant recipients

F Maggi, D Focosi, M Statzu, G Bianco, C Costa… - Scientific reports, 2018 - nature.com
Monitoring the human virome has been recently suggested as a promising and novel area of
research for identifying new biomarkers which would help physicians in the management of …

Torque teno virus as a novel biomarker targeting the efficacy of immunosuppression after lung transplantation

P Jaksch, M Kundi, I Görzer, G Muraközy… - The Journal of …, 2018 - academic.oup.com
Torque teno viruses (TTV) are small DNA-viruses, of the genus Alphatorquevirus, whose
replication is linked to immune status. TTV load may be an indicator for efficacy of IS in lung …