Nanomaterials have much to offer, not only in deciphering innate immune cell biology and
tracking cells, but also in advancing personalized clinical care by providing diagnostic and …

Nanodiagnostics as a field makes use of fundamental advances in nanobiotechnology to
diagnose, characterize and manage disease at the molecular scale. As these strategies …

The foreign body response is an immune-mediated reaction that can lead to the failure of
implanted medical devices and discomfort for the recipient,,,,,. There is a critical need for …

Molecular imaging often relies on the use of targeted and activatable reporters to quantitate
and visualize targets, biological processes, and cells in vivo. The use of optical probes with …

Fluorescence sampling of cellular function is widely used in all aspects of biology, allowing
the visualization of cellular and sub-cellular biological processes with spatial resolutions in …

A bottleneck for immunotherapy of cancer is the immunosuppressive microenvironment in
which the tumor cells proliferate. Cancers harness the immune regulatory mechanism that …

Although cellular therapies hold great promise for the treatment of human disease, results
from several initial clinical trials have not shown a level of efficacy required for their use as a …

OBJECTIVE. In this article, we summarize the progress to date on the use of
superparamagnetic iron oxide nanoparticles (SPIONs) as contrast agents for MRI of …

Proteases are enzymes that cleave peptide bonds in protein substrates. This process can be
important for regulated turnover of a target protein but it can also produce protein fragments …

The pathophysiology of antibody-mediated rejection (AMR) in solid organ transplants is
multifaceted and predominantly caused by antibodies directed against polymorphic donor …