Nerve guide conduits for peripheral nerve injury repair: A review on design, materials and fabrication methods

S Vijayavenkataraman - Acta biomaterialia, 2020 - Elsevier
Peripheral nerves can sustain injuries due to loss of structure and/or function of peripheral
nerves because of accident, trauma and other causes, which leads to partial or complete …

Neural tissue engineering options for peripheral nerve regeneration

X Gu, F Ding, DF Williams - Biomaterials, 2014 - Elsevier
Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to
autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are …

A fully biodegradable and self-electrified device for neuroregenerative medicine

L Wang, C Lu, S Yang, P Sun, Y Wang, Y Guan… - Science …, 2020 - science.org
Peripheral nerve regeneration remains one of the greatest challenges in regenerative
medicine. Deprivation of sensory and/or motor functions often occurs with severe injuries …

FDA approved guidance conduits and wraps for peripheral nerve injury: a review of materials and efficacy

S Kehoe, XF Zhang, D Boyd - Injury, 2012 - Elsevier
Several nerve guidance conduits (NGCs) and nerve protectant wraps are approved by the
US Food and Drug Administration (FDA) for clinical use in peripheral nerve repair. These …

Trends in the design of nerve guidance channels in peripheral nerve tissue engineering

V Chiono, C Tonda-Turo - Progress in neurobiology, 2015 - Elsevier
The current trend of peripheral nerve tissue engineering is the design of advanced nerve
guidance channels (NGCs) acting as physical guidance for regeneration of nerves across …

Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration

X Gu, F Ding, Y Yang, J Liu - Progress in neurobiology, 2011 - Elsevier
Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

Biomaterials for the development of peripheral nerve guidance conduits

AR Nectow, KG Marra, DL Kaplan - Tissue Engineering Part B …, 2012 - liebertpub.com
Currently, surgical treatments for peripheral nerve injury are less than satisfactory. The gold
standard of treatment for peripheral nerve gaps> 5 mm is the autologous nerve graft; …

Current applications and future perspectives of artificial nerve conduits

X Jiang, SH Lim, HQ Mao, SY Chew - Experimental neurology, 2010 - Elsevier
Artificial nerve guide conduits have the advantage over autografts in terms of their
availability and ease of fabrication. However, clinical outcomes associated with the use of …

Peripheral nerve injuries treatment: a systematic review

R Li, Z Liu, Y Pan, L Chen, Z Zhang, L Lu - Cell biochemistry and …, 2014 - Springer
Patients with peripheral nerve injuries, especially severe injury, often face poor nerve
regeneration and incompletely functional recovery, even after surgical nerve repair. Current …

Biomimetic architectures for peripheral nerve repair: a review of biofabrication strategies

PA Wieringa, AR Gonçalves de Pinho… - Advanced …, 2018 - Wiley Online Library
Biofabrication techniques have endeavored to improve the regeneration of the peripheral
nervous system (PNS), but nothing has surpassed the performance of current clinical …