In this review, we describe recent empirical and theoretical work on the extent of linkage
disequilibrium (LD) in the human genome, comparing the predictions of simple population …

Particular alleles at neighbouring loci tend to be co-inherited. For tightly linked loci, this
might lead to associations between alleles in the population—a property known as linkage …

The short arms of the human acrocentric chromosomes 13, 14, 15, 21 and 22 (SAACs) share
large homologous regions, including ribosomal DNA repeats and extended segmental …

Association studies based on linkage disequilibrium (LD) can provide high resolution for
identifying genes that may contribute to phenotypic variation. We report patterns of local and …

Assessing the association between DNA variants and disease has been used widely to
identify regions of the genome and candidate genes that contribute to disease. However …

Individual differences in DNA sequence are the genetic basis of human variability. We have
characterized whole-genome patterns of common human DNA variation by genotyping …

We measured sequence diversity in 21 loci distributed along chromosome 1 of maize (Zea
mays ssp. mays L.). For each locus, we sequenced a common sample of 25 individuals …

Detecting recent selected 'genomic footprints' applies directly to the discovery of disease
genes and in the imputation of the formative events that molded modern population genetic …

Linkage disequilibrium has become important in the context of gene mapping. We argue that
to understand the pattern of association between alleles at different loci, and of DNA …

In this review, we consider the motivation behind contemporary Single Nucleotide
Polymorphism (SNP) initiatives. Many of these initiatives are projected to involve large …