Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital
component of the G protein-coupled receptor (GPCR) family and is found primarily on the …

Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

For several decades, there has been considerable interest in marine‐derived long chain n‐3
fatty acids (n‐3 LCPUFAs) due to their outstanding health benefits. n‐3 LCPUFAs can be …

Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

Background Cognitive deficits are common in patients with sepsis. Previous studies in
sepsis-associated encephalopathy (SAE) implicated the CXC chemokine receptor type …

Background Neuroinflammation has been reported as a potential contributing factor to brain
diseases, and is characterized by activated microglia with release of multiple inflammatory …

Notwithstanding the ongoing debate on their full potential in health and disease, there is
general consensus that n-3 PUFAs play important physiological roles. Increasing dietary n-3 …

Docosahexaenoic acid (DHA) is an essential fatty acid that is recognized as a beneficial
dietary constituent and as a source of the anti-inflammatory specialized proresolving …

N-Docosahexaenoylethanolamine (synaptamide) is an endocannabinoid-like metabolite
endogenously synthesized from docosahexaenoic acid (DHA, 22: 6n-3), the major omega-3 …