The tumor microenvironment is one of the important drivers of tumor development. Cancer-
associated fibroblasts (CAFs) are a major component of the tumor stroma and actively …

Fibroblasts synthesise the extracellular matrix (ECM) such as collagen and elastin, the
excessive accumulation of which can lead to fibrosis and organ dysfunction under …

Bronchopulmonary dysplasia (BPD) is a disease of prematurity related to the arrest of
normal lung development. The objective of this study was to better understand how …

Simple Summary Recent progress in research on the biology of cancer-associated
fibroblasts (CAFs) in pancreatic ductal adenocarcinoma (PDAC) indicates their diverse …

Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with a bleak
prognosis. Mounting evidence suggests that IPF shares bio-molecular similarities with lung …

As a fatal occupational disease with limited therapeutic options, molecular mechanisms
underpinning silicosis are still undefined. Herein, single-cell RNA sequencing of the lung …

Idiopathic pulmonary fibrosis (IPF) is the most common fibrotic form of idiopathic diffuse lung
disease. Due to limited treatment options, IPF patients suffer from poor survival. About ten …

The last 2 years have presented previously unforeseen challenges in pulmonary medicine.
Despite the significant impact of the SARS‐CoV‐2 pandemic on patients, clinicians and …

Cancer-associated fibroblasts (CAFs) are an integral component of the tumor
microenvironment (TME). Most CAFs shape the TME toward an immunosuppressive milieu …

Perivascular mesenchymal cells (PMCs), which include pericytes, give rise to myofibroblasts
that contribute to chronic kidney disease progression. Several PMC markers have been …