In response to major changes in diagnostic algorithms and the publication of mature results
from various large clinical trials, the European Association of Neuro-Oncology (EANO) …

Abstract Purpose of Review Glioblastoma (GBM) is the most common malignant primary
brain tumor, and the available treatment options are limited. This article reviews the recent …

Introduction Hyperthermia therapy (HT) is a recognized treatment modality, that can
sensitize tumors to the effects of radiotherapy (RT) and chemotherapy by heating up tumor …

Research into high linear energy transfer (LET) radiotherapy now spans over half a century,
beginning with helium and deuteron treatment in 1952 and today ranging from fast neutrons …

Simple Summary Carbon-ion radiotherapy is a potential elective treatment option for hypoxic
tumors. Its high linear energy transfer enables enhanced cell killing in radiation-resistant …

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. Despite
an established standard of care including surgical resection, radiation therapy, and …

Although treatment outcomes of glioblastoma, the most malignant central nervous system
(CNS) tumor, has improved in the past decades, it is still incurable, and survival has only …

Malignant glioma remains one of the most aggressive intracranial tumors with devastating
clinical outcomes despite the great advances in conventional treatment approaches …

Purposes Increased number of studies reveal the crucial role of the Cyclic GMP–AMP
synthase/stimulator of interferon genes (cGAS/STING) pathway in anti-tumor immunity. In …

Gliomas are the most common type of primary brain tumor in adults. Glioma treatment
requires a multidisciplinary approach involving surgery, radiotherapy, and chemotherapy …