Hemorrhage is a top cause of death after injury and is the leading cause of potentially
preventable trauma deaths. 1–3 In contrast to other causes of trauma death, such as …

Background The resuscitation of severely injured bleeding patients has evolved into a multi-
modal strategy termed damage control resuscitation (DCR). This guideline evaluates …

The term “shock” originates from “choc,” which was coined by French surgeon Henri
Francois Le Dran in the eighteenth century to describe the destructive impact of gunshot. 1 It …

BACKGROUND American College of Surgeons Trauma Quality Improvement Best Practices
recommends initial massive transfusion (MT) cooler delivery within 15 minutes of protocol …

Essentials An immediate supply of plasma in case of trauma‐induced coagulopathy is
required. The Traucc trial compared French Lyophilised Plasma (FLyP) and Fresh Frozen …

Background Process evaluations are increasingly conducted within pragmatic randomised
controlled trials (RCTs) of health services interventions and provide vital information to …

Massive hemorrhage is a leading cause of death worldwide. During the last decade several
retrospective and some prospective clinical studies have suggested a beneficial effect of …

BACKGROUND Use of universally ABO‐compatible group AB plasma for trauma
resuscitation can be challenging due to supply limitations. Many centers are now using …

Traumatic hemorrhage is the leading cause of preventable death after trauma. Early
transfusion of plasma and balanced transfusion have been shown to optimize survival …

Hemorrhage in the setting of severe trauma is a leading cause of death worldwide. The
pathophysiology of hemorrhage and coagulopathy in severe trauma is complex and remains …