The promise of adolescence: Realizing opportunity for all youth

EP Backes, RJ Bonnie - 2019 - books.google.com
Adolescenceâ€" beginning with the onset of puberty and ending in the mid-20sâ€" is a
critical period of development during which key areas of the brain mature and develop …

Effects of adolescent alcohol consumption on the brain and behaviour

LP Spear - Nature Reviews Neuroscience, 2018 - nature.com
Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

Internet Addiction in adolescence: Neurobiological, psychosocial and clinical issues

L Cerniglia, F Zoratto, S Cimino, G Laviola… - Neuroscience & …, 2017 - Elsevier
Despite it has not been formally included in DSM-5 as a disorder,'Internet addiction (IA)'has
become a worldwide issue. It can be broadly defined as a non-chemical, behavioral …

Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior

LK Bicks, K Yamamuro, ME Flanigan, JM Kim… - Nature …, 2020 - nature.com
Social isolation during the juvenile critical window is detrimental to proper functioning of the
prefrontal cortex (PFC) and establishment of appropriate adult social behaviors. However …

Adolescent obesity and dietary decision making—a brain-health perspective

CJ Lowe, JB Morton, AC Reichelt - The Lancet Child & Adolescent …, 2020 - thelancet.com
Adolescence represents a key period of brain development underpinned by the ongoing
maturation of the prefrontal cortex—a brain region involved in the regulation of behaviour …

[HTML][HTML] Systemic LPS-induced microglial activation results in increased GABAergic tone: a mechanism of protection against neuroinflammation in the medial …

J Jiang, B Tang, L Wang, Q Huo, S Tan… - Brain, behavior, and …, 2022 - Elsevier
Neuroinflammation with excess microglial activation and synaptic dysfunction are early
symptoms of most neurological diseases. However, how microglia-associated …

Long-lasting rescue of network and cognitive dysfunction in a genetic schizophrenia model

A Mukherjee, F Carvalho, S Eliez, P Caroni - Cell, 2019 - cell.com
Although sensitizing processes occur earlier, schizophrenia is diagnosed in young
adulthood, which suggests that it might involve a pathological transition during late brain …

Sex differences in the development of the rodent corticolimbic system

H Premachandran, M Zhao… - Frontiers in …, 2020 - frontiersin.org
In recent years, a growing body of research has shown sex differences in the prevalence
and symptomatology of psychopathologies, such as depression, anxiety, and fear-related …

Adolescent neurodevelopment and substance use: Receptor expression and behavioral consequences

HHA Thorpe, S Hamidullah, BW Jenkins… - Pharmacology & …, 2020 - Elsevier
Adolescence is the transitional period between childhood and adulthood, during which
extensive brain development occurs. Since this period also overlaps with the initiation of …

MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in …

D Dwir, B Giangreco, L Xin, L Tenenbaum… - Molecular …, 2020 - nature.com
Various mechanisms involved in schizophrenia pathophysiology, such as dopamine
dysregulation, glutamate/NMDA receptor dysfunction, neuroinflammation or redox …