Influenza A viruses and zoonotic events—are we creating our own reservoirs?
Zoonotic infections of humans with influenza A viruses (IAVs) from animal reservoirs can
result in severe disease in individuals and, in rare cases, lead to pandemic outbreaks; this is …
result in severe disease in individuals and, in rare cases, lead to pandemic outbreaks; this is …
Influenza A viruses: understanding human host determinants
K Ciminski, GP Chase, M Beer… - Trends in Molecular …, 2021 - cell.com
Previous influenza A virus (IAV) pandemics have invariably been caused by the introduction
of an emergent IAV strain from an animal host into a human population with no or only little …
of an emergent IAV strain from an animal host into a human population with no or only little …
Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo
Neuraminidase (NA) is one of the two influenza virus surface glycoproteins, and antibodies
that target it are an independent correlate of protection. However, our current understanding …
that target it are an independent correlate of protection. However, our current understanding …
[PDF][PDF] The neighborhood of the spike gene is a hotspot for modular intertypic homologous and nonhomologous recombination in coronavirus genomes
M Nikolaidis, P Markoulatos… - Molecular biology …, 2022 - academic.oup.com
Coronaviruses (CoVs) have very large RNA viral genomes with a distinct genomic
architecture of core and accessory open reading frames (ORFs). It is of utmost importance to …
architecture of core and accessory open reading frames (ORFs). It is of utmost importance to …
The influenza A virus genome packaging network—complex, flexible and yet unsolved
C Jakob, R Paul-Stansilaus, M Schwemmle… - Nucleic Acids …, 2022 - academic.oup.com
The genome of influenza A virus (IAV) consists of eight unique viral RNA segments. This
genome organization allows genetic reassortment between co-infecting IAV strains …
genome organization allows genetic reassortment between co-infecting IAV strains …
Emergence of swine influenza A virus, porcine respirovirus 1 and swine orthopneumovirus in porcine respiratory disease in Germany
A Graaf-Rau, C Hennig, K Lillie-Jaschniski… - Emerging Microbes & …, 2023 - Taylor & Francis
Respiratory disease is a significant economic issue in pig farming, with a complex aetiology
that includes swine influenza A viruses (swIAV), which are common in European domestic …
that includes swine influenza A viruses (swIAV), which are common in European domestic …
Reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine results in viruses with zoonotic potential
A Markin, G Ciacci Zanella, ZW Arendsee… - PLoS …, 2023 - journals.plos.org
The 2009 H1N1 pandemic (pdm09) lineage of influenza A virus (IAV) crosses interspecies
barriers with frequent human-to-swine spillovers each year. These spillovers reassort and …
barriers with frequent human-to-swine spillovers each year. These spillovers reassort and …
Experimental infection of pigs and ferrets with “pre-pandemic,” human-adapted, and swine-adapted variants of the H1N1pdm09 influenza A virus reveals significant …
C Kristensen, HA Laybourn, JC Crumpton… - PLoS …, 2023 - journals.plos.org
Influenza A viruses are RNA viruses that cause epidemics in humans and are enzootic in the
pig population globally. In 2009, pig-to-human transmission of a reassortant H1N1 virus …
pig population globally. In 2009, pig-to-human transmission of a reassortant H1N1 virus …
Association of common zoonotic pathogens with concentrated animal feeding operations
Animal farming has intensified significantly in recent decades, with the emergence of
concentrated animal feeding operations (CAFOs) in industrialized nations. The congregation …
concentrated animal feeding operations (CAFOs) in industrialized nations. The congregation …
The genomic landscape of swine influenza A viruses in Southeast Asia
MA Zeller, J Ma, FY Wong, S Tum… - Proceedings of the …, 2023 - National Acad Sciences
Swine are a primary source for the emergence of pandemic influenza A viruses. The
intensification of swine production, along with global trade, has amplified the transmission …
intensification of swine production, along with global trade, has amplified the transmission …