Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

Challenges in the treatment of chronic wounds

RG Frykberg, J Banks - Advances in wound care, 2015 - liebertpub.com
Significance: Chronic wounds include, but are not limited, to diabetic foot ulcers, venous leg
ulcers, and pressure ulcers. They are a challenge to wound care professionals and …

[HTML][HTML] Global vascular guidelines on the management of chronic limb-threatening ischemia

MS Conte, AW Bradbury, P Kolh, JV White… - European Journal of …, 2019 - Elsevier
Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

A Glucose‐Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections

L Chen, S Xing, Y Lei, Q Chen, Z Zou… - Angewandte …, 2021 - Wiley Online Library
The peroxidase‐like activity of nanozymes is promising for chemodynamic therapy by
catalyzing H2O2 into. OH. However, for most nanozymes, this activity is optimal just in acidic …

Current challenges and opportunities in the prevention and management of diabetic foot ulcers

WJ Jeffcoate, L Vileikyte, EJ Boyko… - Diabetes …, 2018 - Am Diabetes Assoc
Diabetic foot ulcers remain a major health care problem. They are common, result in
considerable suffering, frequently recur, and are associated with high mortality, as well as …

Staphylococcal osteomyelitis: disease progression, treatment challenges, and future directions

N Kavanagh, EJ Ryan, A Widaa, G Sexton… - Clinical microbiology …, 2018 - Am Soc Microbiol
Osteomyelitis is an inflammatory bone disease that is caused by an infecting microorganism
and leads to progressive bone destruction and loss. The most common causative species …

Guidelines on the classification of foot ulcers in people with diabetes (IWGDF 2023 update)

M Monteiro‐Soares, EJ Hamilton… - Diabetes/Metabolism …, 2024 - Wiley Online Library
Background This publication represents a scheduled update of the 2019 guidelines of the
International Working Group of the Diabetic Foot (IWGDF) addressing the use of systems to …

Diabetic microvascular disease: an endocrine society scientific statement

EJ Barrett, Z Liu, M Khamaisi, GL King… - The Journal of …, 2017 - academic.oup.com
Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

[PDF][PDF] IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes

BA Lipsky, J Aragón-Sánchez, M Diggle… - Diabetes Metab Res …, 2016 - aogp.com.au
23. Do not select a specific type of dressing for a diabetic foot infection with the aim of
preventing an infection or improving its outcome (strong; high). 24. For diabetic foot …

Diabetic foot ulcer classifications: a critical review

M Monteiro‐Soares, EJ Boyko… - Diabetes/metabolism …, 2020 - Wiley Online Library
Classification and scoring systems can help both clinical management and audit outcomes
of routine care. The aim of this study was to assess published systems of diabetic foot ulcers …