Immunosenescence contributes to a decreased capacity of the immune system to respond
effectively to infections or vaccines in the elderly. The full extent of the biological changes …

We are witnessing the growing menace of both increasing cases of drug-sensitive and drug-
resistant Mycobacterium tuberculosis strains and the challenge to produce the first new …

Elucidation of pathogenicity mechanisms of the most important human-pathogenic fungi,
Aspergillus fumigatus and Candida albicans, has gained great interest in the light of the …

Tuberculosis (TB) is an infectious disease that mainly affects the lungs and spreads to other
organs of the body through the haematogenous route. It is one of the ten major causes of …

The risk of active tuberculosis disease is 15-21 times higher in those coinfected with human
immunodeficiency virus-1 (HIV) compared to tuberculosis alone, and tuberculosis is the …

One problem associated with regimen-based development of antituberculosis (anti-TB)
drugs is the difficulty of a systematic and thorough in vivo evaluation of the large number of …

The borderline between virulence and efficacy in live attenuated vaccine strains is often
blurred and this is also the case for the Bacillus Calmette–Guérin (BCG), the only currently …

Tuberculosis is both highly prevalent across the world and eludes our attempts to control it.
The current bacillus C almette–G uérin vaccine has unreliable protection against adult …

Tuberculosis (TB), a disease caused by bacteria Mycobacterium tuberculosis (Mtb), remains
one of the major infectious diseases of humans with 10 million TB cases and 1.5 million …

Pathogenicity of Aspergillus fumigatus is multifactorial. Thus, global studies are essential for
the understanding of the infection process. Therefore, a data warehouse was established …