Pharmacologically active phytomolecules isolated from traditional antidiabetic plants and their therapeutic role for the management of diabetes mellitus

P Ansari, S Akther, JMA Hannan, V Seidel, NJ Nujat… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a chronic complication that affects people of all ages. The increased
prevalence of diabetes worldwide has led to the development of several synthetic drugs to …

Phytochemical and pharmacological properties of Vernonia amygdalina: a review

OR Alara, NH Abdurahman… - Journal of Chemical …, 2017 - journal.ump.edu.my
Vernonia amygdalina has been a known food and medicinal plants used in Asia and Africa
(West Africa) due to its pharmacological effects (antioxidant, anti-diabetes, antiinflammatory …

[HTML][HTML] Ethanolic extraction of flavonoids, phenolics and antioxidants from Vernonia amygdalina leaf using two-level factorial design

OR Alara, NH Abdurahman, OA Olalere - Journal of King Saud University …, 2020 - Elsevier
Vernonia amygdalina leaves are mostly consumed in Asia and Africa, due to its potential as
a good source of antioxidants. In this study, a two-level factorial design was used to evaluate …

Potential use of the Asteraceae family as a cure for diabetes: A review of ethnopharmacology to modern day drug and nutraceuticals developments

YK Mohanta, AK Mishra, A Nongbet… - Frontiers in …, 2023 - frontiersin.org
The diabetes-associated mortality rate is increasing annually, along with the severity of its
accompanying disorders that impair human health. Worldwide, several medicinal plants are …

[HTML][HTML] Vernonia amygdalina: A folkloric herb with anthelminthic properties

IT Oyeyemi, AA Akinlabi, A Adewumi… - Beni-suef University …, 2018 - Elsevier
Vernonia amygdalina, a widely grown shrub plant in Africa is consumed as vegetable and
has high medicinal value. It has gained wide application in the treatment and management …

Luteolin and Vernodalol as Bioactive Compounds of Leaf and Root Vernonia amygdalina Extracts: Effects on α-Glucosidase, Glycation, ROS, Cell Viability, and In …

FM Djeujo, V Stablum, E Pangrazzi, E Ragazzi… - Pharmaceutics, 2023 - mdpi.com
The aqueous decoctions of Vernonia amygdalina (VA) leaves and roots are widely used in
traditional African medicine as an antidiabetic remedy. The amount of luteolin and …

[HTML][HTML] Anti-inflammatory, anti-nociceptive and antipyretic activity of young and old leaves of Vernonia amygdalina

DB Asante, IT Henneh, DO Acheampong, F Kyei… - Biomedicine & …, 2019 - Elsevier
Background Both young and old leaves of Vernonia amygdalina (VA) are traditionally used
to treat inflammation, pain and fever. However, the efficacy of young and old leaves for …

Therapeutic Benefit of Vernonia amygdalina in the Treatment of Diabetes and Its Associated Complications in Preclinical Studies

DB Asante, GA Wiafe - Journal of Diabetes Research, 2023 - Wiley Online Library
Diabetes mellitus (DM), a complex heterogeneous metabolic disorder characterized by a
defect in the function of insulin, is on the rapid rise globally. Sustained hyperglycemia which …

Anti-Diabetic Potential of Ocimum gratissimum Leaf Fractions in Fortified Diet-Fed Streptozotocin Treated Rat Model of Type-2 Diabetes

SIR Okoduwa, IA Umar, DB James, HM Inuwa - Medicines, 2017 - mdpi.com
Background: Ocimum gratissimum (OG) is used in the traditional management of diabetes in
Nigeria. This study investigated the anti-diabetic potential of OG leaf fractions (OGLF) in a rat …

[HTML][HTML] In vitro and in vivo antidiabetic activity of isolated fraction of Prosopis cineraria against streptozotocin-induced experimental diabetes: A mechanistic study

LK Soni, MP Dobhal, D Arya, K Bhagour… - Biomedicine & …, 2018 - Elsevier
A rapidly increasing incidence of Diabetes mellitus throughout the world is a major concern
in both developed and developing countries and the drawbacks associated with currently …