Electrospinning of chitosan-based solutions for tissue engineering and regenerative medicine

SB Qasim, MS Zafar, S Najeeb, Z Khurshid… - International journal of …, 2018 - mdpi.com
Electrospinning has been used for decades to generate nano-fibres via an electrically
charged jet of polymer solution. This process is established on a spinning technique, using …

Current approaches to bone tissue engineering: the interface between biology and engineering

JJ Li, M Ebied, J Xu, H Zreiqat - Advanced healthcare materials, 2018 - Wiley Online Library
The successful regeneration of bone tissue to replace areas of bone loss in large defects or
at load‐bearing sites remains a significant clinical challenge. Over the past few decades …

Controlling osteoblast morphology and proliferation via surface micro-topographies of implant biomaterials

K Rabel, RJ Kohal, T Steinberg, P Tomakidi… - Scientific reports, 2020 - nature.com
Current research on surface modifications has yielded advanced implant biomaterials.
Various implant surface modifications have been shown to be promising in improving bone …

Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery

SM Willerth, SE Sakiyama-Elbert - StemJournal, 2019 - content.iospress.com
Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

Mechanical properties and morphological alterations in fiber-based scaffolds affecting tissue engineering outcomes

J Dolgin, SN Hanumantharao, S Farias, CG Simon Jr… - Fibers, 2023 - mdpi.com
Electrospinning is a versatile tool used to produce highly customizable nonwoven nanofiber
mats of various fiber diameters, pore sizes, and alignment. It is possible to create …

3D printing of cytocompatible graphene/alginate scaffolds for mimetic tissue constructs

J Li, X Liu, JM Crook, GG Wallace - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Tissue engineering, based on a combination of 3D printing, biomaterials blending and stem
cell technology, offers the potential to establish customized, transplantable autologous …

A bioprinting process supplemented with in situ electrical stimulation directly induces significant myotube formation and myogenesis

WJ Kim, H Lee, CK Lee, JW Kyung… - Advanced Functional …, 2021 - Wiley Online Library
Electric field stimulation has supported biophysical and biological cues for tissue
regeneration approaches to affect cell morphology, alignment, and even cellular phenotypes …

Predicting gene expression using morphological cell responses to nanotopography

MFA Cutiongco, BS Jensen, PM Reynolds… - Nature …, 2020 - nature.com
Cells respond in complex ways to their environment, making it challenging to predict a direct
relationship between the two. A key problem is the lack of informative representations of …

FAK-and YAP/TAZ dependent mechanotransduction pathways are required for enhanced immunomodulatory properties of adipose-derived mesenchymal stem cells …

S Wan, X Fu, Y Ji, M Li, X Shi, Y Wang - Biomaterials, 2018 - Elsevier
Adipose-derived mesenchymal stem cells (ASCs) represent an excellent candidate for
tissue engineering due to their multipotency and paracrine functions. Physical cues provided …

The bumpy road to stem cell therapies: Rational design of surface topographies to dictate stem cell mechanotransduction and fate

J Carthew, JBJ Taylor, MR Garcia-Cruz… - … Applied Materials & …, 2022 - ACS Publications
Cells sense and respond to a variety of physical cues from their surrounding
microenvironment, and these are interpreted through mechanotransductive processes to …