Approaches to achieve high‐level heterologous protein production in plants

SJ Streatfield - Plant biotechnology journal, 2007 - Wiley Online Library
Plants offer an alternative to microbial fermentation and animal cell cultures for the
production of recombinant proteins. For protein pharmaceuticals, plant systems are …

Expression of single-domain antibody in different systems

Y Liu, H Huang - Applied microbiology and biotechnology, 2018 - Springer
Camelid single-domain antibodies (sdAbs, VHHs, or Nanobodies®) are types of antibody
fragments that are composed of the heavy-chain variable domain only. These VHHs …

Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size

X Song, X Meng, H Guo, Q Cheng, Y Jing… - Nature …, 2022 - nature.com
Crop genetic improvement requires balancing complex tradeoffs caused by gene pleiotropy
and linkage drags, as exemplified by IPA1 (Ideal Plant Architecture 1), a typical pleiotropic …

Tuning plant phenotypes by precise, graded downregulation of gene expression

C Xue, F Qiu, Y Wang, B Li, KT Zhao, K Chen… - Nature …, 2023 - nature.com
The ability to control gene expression and generate quantitative phenotypic changes is
essential for breeding new and desired traits into crops. Here we report an efficient, facile …

Nitrate–NRT1. 1B–SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants

B Hu, Z Jiang, W Wang, Y Qiu, Z Zhang, Y Liu, A Li… - Nature plants, 2019 - nature.com
To ensure high crop yields in a sustainable manner, a comprehensive understanding of the
control of nutrient acquisition is required. In particular, the signalling networks controlling the …

Auxin contributes to jasmonate-mediated regulation of abscisic acid signaling during seed germination in Arabidopsis

S Mei, M Zhang, J Ye, J Du, Y Jiang, Y Hu - The Plant Cell, 2023 - academic.oup.com
Abscisic acid (ABA) represses seed germination and postgerminative growth in Arabidopsis
thaliana. Auxin and jasmonic acid (JA) stimulate ABA function; however, the possible …

The long noncoding RNA MdLNC499 bridges MdWRKY1 and MdERF109 function to regulate early-stage light-induced anthocyanin accumulation in apple fruit

H Ma, T Yang, Y Li, J Zhang, T Wu, T Song… - The Plant …, 2021 - academic.oup.com
Anthocyanin pigments contribute to plant coloration and are valuable sources of
antioxidants in the human diet as components of fruits and vegetables. Their production is …

PHOSPHATE STARVATION RESPONSE1 (PHR1) interacts with JASMONATE ZIM-DOMAIN (JAZ) and MYC2 to modulate phosphate deficiency-induced jasmonate …

K He, J Du, X Han, H Li, M Kui, J Zhang, Z Huang… - The Plant …, 2023 - academic.oup.com
Phosphorus (P) is a macronutrient necessary for plant growth and development. Inorganic
phosphate (Pi) deficiency modulates the signaling pathway of the phytohormone jasmonate …

Natural variation of DROT1 confers drought adaptation in upland rice

X Sun, H Xiong, C Jiang, D Zhang, Z Yang… - Nature …, 2022 - nature.com
Upland rice is a distinct ecotype that grows in aerobic environments and tolerates drought
stress. However, the genetic basis of its drought resistance is unclear. Here, using an …

Genome editing of upstream open reading frames enables translational control in plants

H Zhang, X Si, X Ji, R Fan, J Liu, K Chen, D Wang… - Nature …, 2018 - nature.com
Translational regulation by upstream open reading frames (uORFs) is becoming established
as a general mechanism for controlling the amount of protein that is synthesized from …